P16278: Beta-galactosidase

General Information

Protein names	- Beta-galactosidase - 3.2.1.23 {ECO:0000269\|PubMed:15714521, ECO:0000269\|PubMed:19472408, ECO:0000269\|PubMed:24737316, ECO:0000269\|PubMed:2511208, ECO:0000269\|PubMed:25936995, ECO:0000269\|PubMed:3143362, ECO:0000269\|PubMed:8200356} - Acid beta-galactosidase - Lactase - Elastin receptor 1
Gene names	GLB1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P16278

4 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Beta-galactosidase - Isoform 3 of Beta-galactosidase

Sequence View

        10         20         30         40         50         60
MPGFLVRILP LLLVLLLLGP TRGLRNATQR MFEIDYSRDS FLKDGQPFRY ISGSIHYSRV
        70         80         90        100        110        120
PRFYWKDRLL KMKMAGLNAI QTYVPWNFHE PWPGQYQFSE DHDVEYFLRL AHELGLLVIL
       130        140        150        160        170        180
RPGPYICAEW EMGGLPAWLL EKESILLRSS DPDYLAAVDK WLGVLLPKMK PLLYQNGGPV
       190        200        210        220        230        240
ITVQVENEYG SYFACDFDYL RFLQKRFRHH LGDDVVLFTT DGAHKTFLKC GALQGLYTTV
       250        260        270        280        290        300
DFGTGSNITD AFLSQRKCEP KGPLINSEFY TGWLDHWGQP HSTIKTEAVA SSLYDILARG
       310        320        330        340        350        360
ASVNLYMFIG GTNFAYWNGA NSPYAAQPTS YDYDAPLSEA GDLTEKYFAL RNIIQKFEKV
       370        380        390        400        410        420
PEGPIPPSTP KFAYGKVTLE KLKTVGAALD ILCPSGPIKS LYPLTFIQVK QHYGFVLYRT
       430        440        450        460        470        480
TLPQDCSNPA PLSSPLNGVH DRAYVAVDGI PQGVLERNNV ITLNITGKAG ATLDLLVENM
       490        500        510        520        530        540
GRVNYGAYIN DFKGLVSNLT LSSNILTDWT IFPLDTEDAV RSHLGGWGHR DSGHHDEAWA
       550        560        570        580        590        600
HNSSNYTLPA FYMGNFSIPS GIPDLPQDTF IQFPGWTKGQ VWINGFNLGR YWPARGPQLT
       610        620        630        640        650        660
LFVPQHILMT SAPNTITVLE LEWAPCSSDD PELCAVTFVD RPVIGSSVTY DHPSKPVEKR
       670
LMPPPPQKNK DSWLDHV         10         20         30         40         50         60
MPGFLVRILP LLLVLLLLGP TRGLRNATQR MFEIDYSRDS FLKDGQPFRY ISGSIHYSRV
        70         80         90        100        110        120
PRFYWKDRLL KMKMAGLNAI QTYVPWNFHE PWPGQYQFSE DHDVEYFLRL AHELGLLVIL
       130        140        150        160        170        180
RPGPYICAEW EMGGLPAWLL EKESILLRSS DPDYLAAVDK WLGVLLPKMK PLLYQNGGPV
       190        200        210        220        230        240
ITVQVENEYG SYFACDFDYL RFLQKRFRHH LGDDVVLFTT DGAHKTFLKC GALQGLYTTV
       250        260        270        280        290        300
DFGTGSNITD AFLSQRKCEP KGPLINSEFY TGWLDHWGQP HSTIKTEAVA SSLYDILARG
       310        320        330        340        350        360
ASVNLYMFIG GTNFAYWNGA NSPYAAQPTS YDYDAPLSEA GDLTEKYFAL RNIIQKFEKV
       370        380        390        400        410        420
PEGPIPPSTP KFAYGKVTLE KLKTVGAALD ILCPSGPIKS LYPLTFIQVK QHYGFVLYRT
       430        440        450        460        470        480
TLPQDCSNPA PLSSPLNGVH DRAYVAVDGI PQGVLERNNV ITLNITGKAG ATLDLLVENM
       490        500        510        520        530        540
GRVNYGAYIN DFKGLVSNLT LSSNILTDWT IFPLDTEDAV RSHLGGWGHR DSGHHDEAWA
       550        560        570        580        590        600
HNSSNYTLPA FYMGNFSIPS GIPDLPQDTF IQFPGWTKGQ VWINGFNLGR YWPARGPQLT
       610        620        630        640        650        660
LFVPQHILMT SAPNTITVLE LEWAPCSSDD PELCAVTFVD RPVIGSSVTY DHPSKPVEKR
       670
LMPPPPQKNK DSWLDHV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P16278-1-unknown	MPGFLV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt68399
P16278-29-unknown	QRMFEI...	29	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P16278-29-unknown	QRMFEI...	29	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114470
P16278-31-unknown	MFEIDY...	31	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt68400
P16278-31-unknown	MFEIDY...	31	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000382333
P16278-31-unknown	MFEIDY...	31	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000403264
P16278-31-unknown	MFEIDY...	31	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt98526
P16278-132-unknown	MGGLPA...	132	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411769
P16278-132-unknown	MGGLPA...	132	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132485

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QYQFSE	99	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000387989
...QYQFSE	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114069
...AEWEMG	132	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000403264
...AEWEMG	132	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114067
...DFGTGS	245	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411769
...DFGTGS	245	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114065
...AGDLTE	344	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411813
...AGDLTE	344	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114062
...AGDLTE	344	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114063
...WLDHV	677	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...WLDHV	677	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt64017
...WLDHV	677	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt64018

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)