TopFIND 4.0

P16310: Growth hormone receptor

General Information

Protein names
- Growth hormone receptor
- GH receptor
- Somatotropin receptor
- Growth hormone-binding protein
- GH-binding protein
- GHBP
- Serum-binding protein
Gene names Ghr
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P16310

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLWRVFLTL ALAVSSDMFP GSGATPATLG KASPVLQRIN PSLRESSSGK PRFTKCRSPE 
        70         80         90        100        110        120 
LETFSCYWTE GDDHNLKVPG SIQLYYARRI AHEWTPEWKE CPDYVSAGAN SCYFNSSYTS 
       130        140        150        160        170        180 
IWIPYCIKLT TNGDLLDEKC FTVDEIVQPD PPIGLNWTLL NISLPGIRGD IQVSWQPPPS 
       190        200        210        220        230        240 
ADVLKGWIIL EYEIQYKEVN ETKWKTMSPI WSTSVPLYSL RLDKEHEVRV RSRQRSFEKY 
       250        260        270        280        290        300 
SEFSEVLRVT FPQMDTLAAC EEDFRFPWFL IIIFGIFGVA VMLFVVIFSK QQRIKMLILP 
       310        320        330        340        350        360 
PVPVPKIKGI DPDLLKEGKL EEVNTILGIH DNYKPDFYND DSWVEFIELD IDDADEKTEE 
       370        380        390        400        410        420 
SDTDRLLSDD QEKSAGILGA KDDDSGRTSC YDPDILDTDF HTSDMCDGTS EFAQPQKLKA 
       430        440        450        460        470        480 
EADLLCLDQK NLKNSPYDAS LGSLHPSITL TMEDKPQPLL GSETESTHQL PSTPMSSPVS 
       490        500        510        520        530        540 
LANIDFYAQV SDITPAGGVV LSPGQKIKAG LAQGNTQLEV AAPCQENYSM NSAYFCESDA 
       550        560        570        580        590        600 
KKCIAAAPHM EATTCVKPSF NQEDIYITTE SLTTTARMSE TADTAPDAEP VPDYTTVHTV 
       610        620        630    
KSPRGLILNA TALPLPDKKK FLSSCGYVST DQLNKIMQ

Isoforms

- Isoform 2 of Growth hormone receptor

Sequence View

        10         20         30         40         50         60 
MDLWRVFLTL ALAVSSDMFP GSGATPATLG KASPVLQRIN PSLRESSSGK PRFTKCRSPE 
        70         80         90        100        110        120 
LETFSCYWTE GDDHNLKVPG SIQLYYARRI AHEWTPEWKE CPDYVSAGAN SCYFNSSYTS 
       130        140        150        160        170        180 
IWIPYCIKLT TNGDLLDEKC FTVDEIVQPD PPIGLNWTLL NISLPGIRGD IQVSWQPPPS 
       190        200        210        220        230        240 
ADVLKGWIIL EYEIQYKEVN ETKWKTMSPI WSTSVPLYSL RLDKEHEVRV RSRQRSFEKY 
       250        260        270        280        290        300 
SEFSEVLRVT FPQMDTLAAC EEDFRFPWFL IIIFGIFGVA VMLFVVIFSK QQRIKMLILP 
       310        320        330        340        350        360 
PVPVPKIKGI DPDLLKEGKL EEVNTILGIH DNYKPDFYND DSWVEFIELD IDDADEKTEE 
       370        380        390        400        410        420 
SDTDRLLSDD QEKSAGILGA KDDDSGRTSC YDPDILDTDF HTSDMCDGTS EFAQPQKLKA 
       430        440        450        460        470        480 
EADLLCLDQK NLKNSPYDAS LGSLHPSITL TMEDKPQPLL GSETESTHQL PSTPMSSPVS 
       490        500        510        520        530        540 
LANIDFYAQV SDITPAGGVV LSPGQKIKAG LAQGNTQLEV AAPCQENYSM NSAYFCESDA 
       550        560        570        580        590        600 
KKCIAAAPHM EATTCVKPSF NQEDIYITTE SLTTTARMSE TADTAPDAEP VPDYTTVHTV 
       610        620        630    
KSPRGLILNA TALPLPDKKK FLSSCGYVST DQLNKIMQ



Filter Information:


(REFRESH)

Directness:


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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P16310-1-unknown MDLWRV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192688
    P16310-19-unknown FPGSGA... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P16310-19-unknown FPGSGA... 19 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt195164

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PQMDTL 256 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...NKIMQ 638 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)