TopFIND 4.0

P16382: Interleukin-4 receptor subunit alpha

General Information

Protein names
- Interleukin-4 receptor subunit alpha
- IL-4 receptor subunit alpha
- IL-4R subunit alpha
- IL-4R-alpha
- IL-4RA
- CD124
- Soluble interleukin-4 receptor subunit alpha
- Soluble IL-4 receptor subunit alpha
- Soluble IL-4R-alpha
- sIL4Ralpha/prot
- IL-4-binding protein
- IL4-BP

Gene names Il4r
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P16382

3

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGRLCTKFLT SVGCLILLLV TGSGSIKVLG EPTCFSDYIR TSTCEWFLDS AVDCSSQLCL 
        70         80         90        100        110        120 
HYRLMFFEFS ENLTCIPRNS ASTVCVCHME MNRPVQSDRY QMELWAEHRQ LWQGSFSPSG 
       130        140        150        160        170        180 
NVKPLAPDNL TLHTNVSDEW LLTWNNLYPS NNLLYKDLIS MVNISREDNP AEFIVYNVTY 
       190        200        210        220        230        240 
KEPRLSFPIN ILMSGVYYTA RVRVRSQILT GTWSEWSPSI TWYNHFQLPL IQRLPLGVTI 
       250        260        270        280        290        300 
SCLCIPLFCL FCYFSITKIK KIWWDQIPTP ARSPLVAIII QDAQVPLWDK QTRSQESTKY 
       310        320        330        340        350        360 
PHWKTCLDKL LPCLLKHRVK KKTDFPKAAP TKSLQSPGKA GWCPMEVSRT VLWPENVSVS 
       370        380        390        400        410        420 
VVRCMELFEA PVQNVEEEED EIVKEDLSMS PENSGGCGFQ ESQADIMARL TENLFSDLLE 
       430        440        450        460        470        480 
AENGGLGQSA LAESCSPLPS GSGQASVSWA CLPMGPSEEA TCQVTEQPSH PGPLSGSPAQ 
       490        500        510        520        530        540 
SAPTLACTQV PLVLADNPAY RSFSDCCSPA PNPGELAPEQ QQADHLEEEE PPSPADPHSS 
       550        560        570        580        590        600 
GPPMQPVESW EQILHMSVLQ HGAAAGSTPA PAGGYQEFVQ AVKQGAAQDP GVPGVRPSGD 
       610        620        630        640        650        660 
PGYKAFSSLL SSNGIRGDTA AAGTDDGHGG YKPFQNPVPN QSPSSVPLFT FGLDTELSPS 
       670        680        690        700        710        720 
PLNSDPPKSP PECLGLELGL KGGDWVKAPP PADQVPKPFG DDLGFGIVYS SLTCHLCGHL 
       730        740        750        760        770        780 
KQHHSQEEGG QSPIVASPGC GCCYDDRSPS LGSLSGALES CPEGIPPEAN LMSAPKTPSN 
       790        800        810    
LSGEGKGPGH SPVPSQTTEV PVGALGIAVS 

Isoforms

- Isoform 2 of Interleukin-4 receptor subunit alpha - Isoform 3 of Interleukin-4 receptor subunit alpha

Sequence View

        10         20         30         40         50         60 
MGRLCTKFLT SVGCLILLLV TGSGSIKVLG EPTCFSDYIR TSTCEWFLDS AVDCSSQLCL 
        70         80         90        100        110        120 
HYRLMFFEFS ENLTCIPRNS ASTVCVCHME MNRPVQSDRY QMELWAEHRQ LWQGSFSPSG 
       130        140        150        160        170        180 
NVKPLAPDNL TLHTNVSDEW LLTWNNLYPS NNLLYKDLIS MVNISREDNP AEFIVYNVTY 
       190        200        210        220        230        240 
KEPRLSFPIN ILMSGVYYTA RVRVRSQILT GTWSEWSPSI TWYNHFQLPL IQRLPLGVTI 
       250        260        270        280        290        300 
SCLCIPLFCL FCYFSITKIK KIWWDQIPTP ARSPLVAIII QDAQVPLWDK QTRSQESTKY 
       310        320        330        340        350        360 
PHWKTCLDKL LPCLLKHRVK KKTDFPKAAP TKSLQSPGKA GWCPMEVSRT VLWPENVSVS 
       370        380        390        400        410        420 
VVRCMELFEA PVQNVEEEED EIVKEDLSMS PENSGGCGFQ ESQADIMARL TENLFSDLLE 
       430        440        450        460        470        480 
AENGGLGQSA LAESCSPLPS GSGQASVSWA CLPMGPSEEA TCQVTEQPSH PGPLSGSPAQ 
       490        500        510        520        530        540 
SAPTLACTQV PLVLADNPAY RSFSDCCSPA PNPGELAPEQ QQADHLEEEE PPSPADPHSS 
       550        560        570        580        590        600 
GPPMQPVESW EQILHMSVLQ HGAAAGSTPA PAGGYQEFVQ AVKQGAAQDP GVPGVRPSGD 
       610        620        630        640        650        660 
PGYKAFSSLL SSNGIRGDTA AAGTDDGHGG YKPFQNPVPN QSPSSVPLFT FGLDTELSPS 
       670        680        690        700        710        720 
PLNSDPPKSP PECLGLELGL KGGDWVKAPP PADQVPKPFG DDLGFGIVYS SLTCHLCGHL 
       730        740        750        760        770        780 
KQHHSQEEGG QSPIVASPGC GCCYDDRSPS LGSLSGALES CPEGIPPEAN LMSAPKTPSN 
       790        800        810    
LSGEGKGPGH SPVPSQTTEV PVGALGIAVS          10         20         30         40         50         60 
MGRLCTKFLT SVGCLILLLV TGSGSIKVLG EPTCFSDYIR TSTCEWFLDS AVDCSSQLCL 
        70         80         90        100        110        120 
HYRLMFFEFS ENLTCIPRNS ASTVCVCHME MNRPVQSDRY QMELWAEHRQ LWQGSFSPSG 
       130        140        150        160        170        180 
NVKPLAPDNL TLHTNVSDEW LLTWNNLYPS NNLLYKDLIS MVNISREDNP AEFIVYNVTY 
       190        200        210        220        230        240 
KEPRLSFPIN ILMSGVYYTA RVRVRSQILT GTWSEWSPSI TWYNHFQLPL IQRLPLGVTI 
       250        260        270        280        290        300 
SCLCIPLFCL FCYFSITKIK KIWWDQIPTP ARSPLVAIII QDAQVPLWDK QTRSQESTKY 
       310        320        330        340        350        360 
PHWKTCLDKL LPCLLKHRVK KKTDFPKAAP TKSLQSPGKA GWCPMEVSRT VLWPENVSVS 
       370        380        390        400        410        420 
VVRCMELFEA PVQNVEEEED EIVKEDLSMS PENSGGCGFQ ESQADIMARL TENLFSDLLE 
       430        440        450        460        470        480 
AENGGLGQSA LAESCSPLPS GSGQASVSWA CLPMGPSEEA TCQVTEQPSH PGPLSGSPAQ 
       490        500        510        520        530        540 
SAPTLACTQV PLVLADNPAY RSFSDCCSPA PNPGELAPEQ QQADHLEEEE PPSPADPHSS 
       550        560        570        580        590        600 
GPPMQPVESW EQILHMSVLQ HGAAAGSTPA PAGGYQEFVQ AVKQGAAQDP GVPGVRPSGD 
       610        620        630        640        650        660 
PGYKAFSSLL SSNGIRGDTA AAGTDDGHGG YKPFQNPVPN QSPSSVPLFT FGLDTELSPS 
       670        680        690        700        710        720 
PLNSDPPKSP PECLGLELGL KGGDWVKAPP PADQVPKPFG DDLGFGIVYS SLTCHLCGHL 
       730        740        750        760        770        780 
KQHHSQEEGG QSPIVASPGC GCCYDDRSPS LGSLSGALES CPEGIPPEAN LMSAPKTPSN 
       790        800        810    
LSGEGKGPGH SPVPSQTTEV PVGALGIAVS 



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)