P16422: Epithelial cell adhesion molecule
| Protein names | - Epithelial cell adhesion molecule - Ep-CAM - Adenocarcinoma-associated antigen - Cell surface glycoprotein Trop-1 - Epithelial cell surface antigen - Epithelial glycoprotein - EGP - Epithelial glycoprotein 314 - EGP314 - hEGP314 - KS 1/4 antigen - KSA - Major gastrointestinal tumor-associated protein GA733-2 - Tumor-associated calcium signal transducer 1 - CD326 |
|---|---|
| Gene names | EPCAM |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P16422 |
2
N-termini
3
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAPPQVLAFG LLLAAATATF AAAQEECVCE NYKLAVNCFV NNNRQCQCTS VGAQNTVICS
70 80 90 100 110 120
KLAAKCLVMK AEMNGSKLGR RAKPEGALQN NDGLYDPDCD ESGLFKAKQC NGTSMCWCVN
130 140 150 160 170 180
TAGVRRTDKD TEITCSERVR TYWIIIELKH KAREKPYDSK SLRTALQKEI TTRYQLDPKF
190 200 210 220 230 240
ITSILYENNV ITIDLVQNSS QKTQNDVDIA DVAYYFEKDV KGESLFHSKK MDLTVNGEQL
250 260 270 280 290 300
DLDPGQTLIY YVDEKAPEFS MQGLKAGVIA VIVVVVIAVV AGIVVLVISR KKRMAKYEKA
310
EIKEMGEMHR ELNA
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P16422-24-unknown | QEECVC... | 24 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P16422-82-unknown | AKPEGA... | 82 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16309 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...KLGRRA | 81 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16309 | |||
| ...VNTAGV | 123 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000389028 | |||
| ...RELNA | 314 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| KLK4_HUMAN | 81 | GRRA.|.AKPE | inferred from experiment | unknown | MEROPS | Nelson PS | Matsumura M et al.:Substrates of the prostate-spec... (S01.251) | 15389820, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|