P16471: Prolactin receptor

General Information

Protein names	- Prolactin receptor - PRL-R
Gene names	PRLR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P16471

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Prolactin receptor - Isoform 3 of Prolactin receptor - Isoform 4 of Prolactin receptor - Isoform 5 of Prolactin receptor - Isoform 6 of Prolactin receptor - Isoform 7 of Prolactin receptor - Isoform 8 of Prolactin receptor - Isoform 9 of Prolactin receptor

Sequence View

        10         20         30         40         50         60
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY
        70         80         90        100        110        120
SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD
       130        140        150        160        170        180
VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW
       190        200        210        220        230        240
EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS
       250        260        270        280        290        300
VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD
       310        320        330        340        350        360
FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL
       370        380        390        400        410        420
SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ
       430        440        450        460        470        480
PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE
       490        500        510        520        530        540
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP
       550        560        570        580        590        600
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS
       610        620
KCRLQLGGLD YLDPACFTHS FH         10         20         30         40         50         60
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY
        70         80         90        100        110        120
SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD
       130        140        150        160        170        180
VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW
       190        200        210        220        230        240
EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS
       250        260        270        280        290        300
VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD
       310        320        330        340        350        360
FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL
       370        380        390        400        410        420
SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ
       430        440        450        460        470        480
PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE
       490        500        510        520        530        540
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP
       550        560        570        580        590        600
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS
       610        620
KCRLQLGGLD YLDPACFTHS FH         10         20         30         40         50         60
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY
        70         80         90        100        110        120
SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD
       130        140        150        160        170        180
VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW
       190        200        210        220        230        240
EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS
       250        260        270        280        290        300
VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD
       310        320        330        340        350        360
FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL
       370        380        390        400        410        420
SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ
       430        440        450        460        470        480
PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE
       490        500        510        520        530        540
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP
       550        560        570        580        590        600
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS
       610        620
KCRLQLGGLD YLDPACFTHS FH         10         20         30         40         50         60
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY
        70         80         90        100        110        120
SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD
       130        140        150        160        170        180
VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW
       190        200        210        220        230        240
EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS
       250        260        270        280        290        300
VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD
       310        320        330        340        350        360
FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL
       370        380        390        400        410        420
SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ
       430        440        450        460        470        480
PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE
       490        500        510        520        530        540
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP
       550        560        570        580        590        600
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS
       610        620
KCRLQLGGLD YLDPACFTHS FH         10         20         30         40         50         60
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY
        70         80         90        100        110        120
SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD
       130        140        150        160        170        180
VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW
       190        200        210        220        230        240
EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS
       250        260        270        280        290        300
VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD
       310        320        330        340        350        360
FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL
       370        380        390        400        410        420
SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ
       430        440        450        460        470        480
PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE
       490        500        510        520        530        540
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP
       550        560        570        580        590        600
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS
       610        620
KCRLQLGGLD YLDPACFTHS FH         10         20         30         40         50         60
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY
        70         80         90        100        110        120
SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD
       130        140        150        160        170        180
VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW
       190        200        210        220        230        240
EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS
       250        260        270        280        290        300
VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD
       310        320        330        340        350        360
FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL
       370        380        390        400        410        420
SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ
       430        440        450        460        470        480
PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE
       490        500        510        520        530        540
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP
       550        560        570        580        590        600
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS
       610        620
KCRLQLGGLD YLDPACFTHS FH         10         20         30         40         50         60
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY
        70         80         90        100        110        120
SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD
       130        140        150        160        170        180
VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW
       190        200        210        220        230        240
EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS
       250        260        270        280        290        300
VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD
       310        320        330        340        350        360
FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL
       370        380        390        400        410        420
SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ
       430        440        450        460        470        480
PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE
       490        500        510        520        530        540
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP
       550        560        570        580        590        600
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS
       610        620
KCRLQLGGLD YLDPACFTHS FH         10         20         30         40         50         60
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY
        70         80         90        100        110        120
SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD
       130        140        150        160        170        180
VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW
       190        200        210        220        230        240
EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS
       250        260        270        280        290        300
VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD
       310        320        330        340        350        360
FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL
       370        380        390        400        410        420
SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ
       430        440        450        460        470        480
PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE
       490        500        510        520        530        540
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP
       550        560        570        580        590        600
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS
       610        620
KCRLQLGGLD YLDPACFTHS FH

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P16471-1-unknown	MKENVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86220
P16471-1-unknown	MKENVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86221
P16471-1-unknown	MKENVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86222
P16471-1-unknown	MKENVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86223
P16471-1-unknown	MKENVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86224
P16471-1-unknown	MKENVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86225
P16471-1-unknown	MKENVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86227
P16471-25-unknown	QLPPGK...	25	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P16471-25-unknown	QLPPGK...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113893
P16471-25-unknown	QLPPGK...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113894
P16471-25-unknown	QLPPGK...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113895
P16471-25-unknown	QLPPGK...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113896
P16471-25-unknown	QLPPGK...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113897
P16471-25-unknown	QLPPGK...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113898
P16471-72-unknown	MHECPD...	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86226
P16471-72-unknown	MHECPD...	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107668
P16471-72-unknown	MHECPD...	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107669
P16471-72-unknown	MHECPD...	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107670
P16471-72-unknown	MHECPD...	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107671
P16471-72-unknown	MHECPD...	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107672
P16471-72-unknown	MHECPD...	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107673

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...THSFH	622	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...THSFH	622	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt81838

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)