TopFIND 4.0

P16599: Tumor necrosis factor

General Information

Protein names
- Tumor necrosis factor
- Cachectin
- TNF-alpha
- Tumor necrosis factor ligand superfamily member 2
- TNF-a
- Tumor necrosis factor, membrane form
- N-terminal fragment
- NTF
- Intracellular domain 1
- ICD1
- Intracellular domain 2
- ICD2
- C-domain 1
- C-domain 2
- Tumor necrosis factor, soluble form
Gene names Tnf
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P16599

4

N-termini

4

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSTESMIRDV ELAEEALPKK MGGLQNSRRC LCLSLFSFLL VAGATTLFCL LNFGVIGPNK 
        70         80         90        100        110        120 
EEKFPNGLPL ISSMAQTLTL RSSSQNSSDK PVAHVVANHQ AEEQLEWLSQ RANALLANGM 
       130        140        150        160        170        180 
DLKDNQLVVP ADGLYLIYSQ VLFKGQGCPD YVLLTHTVSR FAISYQEKVS LLSAIKSPCP 
       190        200        210        220        230    
KDTPEGAELK PWYEPMYLGG VFQLEKGDLL SAEVNLPKYL DITESGQVYF GVIAL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P16599-1-unknown MSTESM... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P16599-50-unknown LLNFGV... 50 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P16599-52-unknown NFGVIG... 52 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P16599-80-unknown LRSSSQ... 80 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)