P16871: Interleukin-7 receptor subunit alpha

General Information

Protein names	- Interleukin-7 receptor subunit alpha - IL-7 receptor subunit alpha - IL-7R subunit alpha - IL-7R-alpha - IL-7RA - CDw127 - CD127
Gene names	IL7R
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P16871

3 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 3 of Interleukin-7 receptor subunit alpha - Isoform 4 of Interleukin-7 receptor subunit alpha - Isoform 2 of Interleukin-7 receptor subunit alpha - Isoform 3 of Interleukin-7 receptor subunit alpha - Isoform 4 of Interleukin-7 receptor subunit alpha - Isoform 2 of Interleukin-7 receptor subunit alpha

Sequence View

        10         20         30         40         50         60
MTILGTTFGM VFSLLQVVSG ESGYAQNGDL EDAELDDYSF SCYSQLEVNG SQHSLTCAFE
        70         80         90        100        110        120
DPDVNITNLE FEICGALVEV KCLNFRKLQE IYFIETKKFL LIGKSNICVK VGEKSLTCKK
       130        140        150        160        170        180
IDLTTIVKPE APFDLSVVYR EGANDFVVTF NTSHLQKKYV KVLMHDVAYR QEKDENKWTH
       190        200        210        220        230        240
VNLSSTKLTL LQRKLQPAAM YEIKVRSIPD HYFKGFWSEW SPSYYFRTPE INNSSGEMDP
       250        260        270        280        290        300
ILLTISILSF FSVALLVILA CVLWKKRIKP IVWPSLPDHK KTLEHLCKKP RKNLNVSFNP
       310        320        330        340        350        360
ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP SEDVVITPES
       370        380        390        400        410        420
FGRDSSLTCL AGNVSACDAP ILSSSRSLDC RESGKNGPHV YQDLLLSLGT TNSTLPPPFS
       430        440        450
LQSGILTLNP VAQGQPILTS LGSNQEEAYV TMSSFYQNQ         10         20         30         40         50         60
MTILGTTFGM VFSLLQVVSG ESGYAQNGDL EDAELDDYSF SCYSQLEVNG SQHSLTCAFE
        70         80         90        100        110        120
DPDVNITNLE FEICGALVEV KCLNFRKLQE IYFIETKKFL LIGKSNICVK VGEKSLTCKK
       130        140        150        160        170        180
IDLTTIVKPE APFDLSVVYR EGANDFVVTF NTSHLQKKYV KVLMHDVAYR QEKDENKWTH
       190        200        210        220        230        240
VNLSSTKLTL LQRKLQPAAM YEIKVRSIPD HYFKGFWSEW SPSYYFRTPE INNSSGEMDP
       250        260        270        280        290        300
ILLTISILSF FSVALLVILA CVLWKKRIKP IVWPSLPDHK KTLEHLCKKP RKNLNVSFNP
       310        320        330        340        350        360
ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP SEDVVITPES
       370        380        390        400        410        420
FGRDSSLTCL AGNVSACDAP ILSSSRSLDC RESGKNGPHV YQDLLLSLGT TNSTLPPPFS
       430        440        450
LQSGILTLNP VAQGQPILTS LGSNQEEAYV TMSSFYQNQ         10         20         30         40         50         60
MTILGTTFGM VFSLLQVVSG ESGYAQNGDL EDAELDDYSF SCYSQLEVNG SQHSLTCAFE
        70         80         90        100        110        120
DPDVNITNLE FEICGALVEV KCLNFRKLQE IYFIETKKFL LIGKSNICVK VGEKSLTCKK
       130        140        150        160        170        180
IDLTTIVKPE APFDLSVVYR EGANDFVVTF NTSHLQKKYV KVLMHDVAYR QEKDENKWTH
       190        200        210        220        230        240
VNLSSTKLTL LQRKLQPAAM YEIKVRSIPD HYFKGFWSEW SPSYYFRTPE INNSSGEMDP
       250        260        270        280        290        300
ILLTISILSF FSVALLVILA CVLWKKRIKP IVWPSLPDHK KTLEHLCKKP RKNLNVSFNP
       310        320        330        340        350        360
ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP SEDVVITPES
       370        380        390        400        410        420
FGRDSSLTCL AGNVSACDAP ILSSSRSLDC RESGKNGPHV YQDLLLSLGT TNSTLPPPFS
       430        440        450
LQSGILTLNP VAQGQPILTS LGSNQEEAYV TMSSFYQNQ         10         20         30         40         50         60
MTILGTTFGM VFSLLQVVSG ESGYAQNGDL EDAELDDYSF SCYSQLEVNG SQHSLTCAFE
        70         80         90        100        110        120
DPDVNITNLE FEICGALVEV KCLNFRKLQE IYFIETKKFL LIGKSNICVK VGEKSLTCKK
       130        140        150        160        170        180
IDLTTIVKPE APFDLSVVYR EGANDFVVTF NTSHLQKKYV KVLMHDVAYR QEKDENKWTH
       190        200        210        220        230        240
VNLSSTKLTL LQRKLQPAAM YEIKVRSIPD HYFKGFWSEW SPSYYFRTPE INNSSGEMDP
       250        260        270        280        290        300
ILLTISILSF FSVALLVILA CVLWKKRIKP IVWPSLPDHK KTLEHLCKKP RKNLNVSFNP
       310        320        330        340        350        360
ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP SEDVVITPES
       370        380        390        400        410        420
FGRDSSLTCL AGNVSACDAP ILSSSRSLDC RESGKNGPHV YQDLLLSLGT TNSTLPPPFS
       430        440        450
LQSGILTLNP VAQGQPILTS LGSNQEEAYV TMSSFYQNQ         10         20         30         40         50         60
MTILGTTFGM VFSLLQVVSG ESGYAQNGDL EDAELDDYSF SCYSQLEVNG SQHSLTCAFE
        70         80         90        100        110        120
DPDVNITNLE FEICGALVEV KCLNFRKLQE IYFIETKKFL LIGKSNICVK VGEKSLTCKK
       130        140        150        160        170        180
IDLTTIVKPE APFDLSVVYR EGANDFVVTF NTSHLQKKYV KVLMHDVAYR QEKDENKWTH
       190        200        210        220        230        240
VNLSSTKLTL LQRKLQPAAM YEIKVRSIPD HYFKGFWSEW SPSYYFRTPE INNSSGEMDP
       250        260        270        280        290        300
ILLTISILSF FSVALLVILA CVLWKKRIKP IVWPSLPDHK KTLEHLCKKP RKNLNVSFNP
       310        320        330        340        350        360
ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP SEDVVITPES
       370        380        390        400        410        420
FGRDSSLTCL AGNVSACDAP ILSSSRSLDC RESGKNGPHV YQDLLLSLGT TNSTLPPPFS
       430        440        450
LQSGILTLNP VAQGQPILTS LGSNQEEAYV TMSSFYQNQ         10         20         30         40         50         60
MTILGTTFGM VFSLLQVVSG ESGYAQNGDL EDAELDDYSF SCYSQLEVNG SQHSLTCAFE
        70         80         90        100        110        120
DPDVNITNLE FEICGALVEV KCLNFRKLQE IYFIETKKFL LIGKSNICVK VGEKSLTCKK
       130        140        150        160        170        180
IDLTTIVKPE APFDLSVVYR EGANDFVVTF NTSHLQKKYV KVLMHDVAYR QEKDENKWTH
       190        200        210        220        230        240
VNLSSTKLTL LQRKLQPAAM YEIKVRSIPD HYFKGFWSEW SPSYYFRTPE INNSSGEMDP
       250        260        270        280        290        300
ILLTISILSF FSVALLVILA CVLWKKRIKP IVWPSLPDHK KTLEHLCKKP RKNLNVSFNP
       310        320        330        340        350        360
ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP SEDVVITPES
       370        380        390        400        410        420
FGRDSSLTCL AGNVSACDAP ILSSSRSLDC RESGKNGPHV YQDLLLSLGT TNSTLPPPFS
       430        440        450
LQSGILTLNP VAQGQPILTS LGSNQEEAYV TMSSFYQNQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P16871-1-unknown	MTILGT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77803
P16871-1-unknown	MTILGT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77804
P16871-1-unknown	MTILGT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77805
P16871-21-unknown	ESGYAQ...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P16871-21-unknown	ESGYAQ...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112715
P16871-21-unknown	ESGYAQ...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112716
P16871-21-unknown	ESGYAQ...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112717
P16871-198-unknown	AAMYEI...	198	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000426069
P16871-198-unknown	AAMYEI...	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt130794
P16871-198-unknown	AAMYEI...	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt130795
P16871-198-unknown	AAMYEI...	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt130796

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VNGSQH	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000425538
...VNGSQH	52	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110468
...VNGSQH	52	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110469
...VNGSQH	52	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110470
...LTCAFE	59	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000426426
...LTCAFE	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110464
...LTCAFE	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110465
...LTCAFE	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110466
...LTSLGS	442	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000420923
...FYQNQ	459	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)