TopFIND 4.0

P16882: Growth hormone receptor

General Information

Protein names
- Growth hormone receptor
- GH receptor
- Somatotropin receptor
- Growth hormone-binding protein
- GH-binding protein
- GHBP
- Serum-binding protein
Gene names Ghr
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P16882

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLCQVFLTL ALAVTSSTFS GSEATPATLG KASPVLQRIN PSLGTSSSGK PRFTKCRSPE 
        70         80         90        100        110        120 
LETFSCYWTE GDNPDLKTPG SIQLYYAKRE SQRQAARIAH EWTQEWKECP DYVSAGKNSC 
       130        140        150        160        170        180 
YFNSSYTSIW IPYCIKLTTN GDLLDQKCFT VDEIVQPDPP IGLNWTLLNI SLTGIRGDIQ 
       190        200        210        220        230        240 
VSWQPPPNAD VLKGWIILEY EIQYKEVNES KWKVMGPIWL TYCPVYSLRM DKEHEVRVRS 
       250        260        270        280        290        300 
RQRSFEKYSE FSEVLRVIFP QTNILEACEE DIQFPWFLII IFGIFGVAVM LFVVIFSKQQ 
       310        320        330        340        350        360 
RIKMLILPPV PVPKIKGIDP DLLKEGKLEE VNTILGIHDN YKPDFYNDDS WVEFIELDID 
       370        380        390        400        410        420 
EADVDEKTEG SDTDRLLSND HEKSAGILGA KDDDSGRTSC YDPDILDTDF HTSDMCDGTL 
       430        440        450        460        470        480 
KFRQSQKLNM EADLLCLDQK NLKNLPYDAS LGSLHPSITQ TVEENKPQPL LSSETEATHQ 
       490        500        510        520        530        540 
LASTPMSNPT SLANIDFYAQ VSDITPAGGD VLSPGQKIKA GIAQGNTQRE VATPCQENYS 
       550        560        570        580        590        600 
MNSAYFCESD AKKCIAVARR MEATSCIKPS FNQEDIYITT ESLTTTAQMS ETADIAPDAE 
       610        620        630        640        650    
MSVPDYTTVH TVQSPRGLIL NATALPLPDK KNFPSSCGYV STDQLNKIMQ 

Isoforms

- Isoform 2 of Growth hormone receptor

Sequence View

        10         20         30         40         50         60 
MDLCQVFLTL ALAVTSSTFS GSEATPATLG KASPVLQRIN PSLGTSSSGK PRFTKCRSPE 
        70         80         90        100        110        120 
LETFSCYWTE GDNPDLKTPG SIQLYYAKRE SQRQAARIAH EWTQEWKECP DYVSAGKNSC 
       130        140        150        160        170        180 
YFNSSYTSIW IPYCIKLTTN GDLLDQKCFT VDEIVQPDPP IGLNWTLLNI SLTGIRGDIQ 
       190        200        210        220        230        240 
VSWQPPPNAD VLKGWIILEY EIQYKEVNES KWKVMGPIWL TYCPVYSLRM DKEHEVRVRS 
       250        260        270        280        290        300 
RQRSFEKYSE FSEVLRVIFP QTNILEACEE DIQFPWFLII IFGIFGVAVM LFVVIFSKQQ 
       310        320        330        340        350        360 
RIKMLILPPV PVPKIKGIDP DLLKEGKLEE VNTILGIHDN YKPDFYNDDS WVEFIELDID 
       370        380        390        400        410        420 
EADVDEKTEG SDTDRLLSND HEKSAGILGA KDDDSGRTSC YDPDILDTDF HTSDMCDGTL 
       430        440        450        460        470        480 
KFRQSQKLNM EADLLCLDQK NLKNLPYDAS LGSLHPSITQ TVEENKPQPL LSSETEATHQ 
       490        500        510        520        530        540 
LASTPMSNPT SLANIDFYAQ VSDITPAGGD VLSPGQKIKA GIAQGNTQRE VATPCQENYS 
       550        560        570        580        590        600 
MNSAYFCESD AKKCIAVARR MEATSCIKPS FNQEDIYITT ESLTTTAQMS ETADIAPDAE 
       610        620        630        640        650    
MSVPDYTTVH TVQSPRGLIL NATALPLPDK KNFPSSCGYV STDQLNKIMQ 



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(REFRESH)

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Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P16882-1-unknown MDLCQV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75973
    P16882-25-unknown TPATLG... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P16882-25-unknown TPATLG... 25 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113710

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)