P16930: Fumarylacetoacetase

General Information

Protein names	- Fumarylacetoacetase - FAA - 3.7.1.2 {ECO:0000250\|UniProtKB:P35505} - Beta-diketonase - Fumarylacetoacetate hydrolase
Gene names	FAH
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P16930

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSFIPVAEDS DFPIHNLPYG VFSTRGDPRP RIGVAIGDQI LDLSIIKHLF TGPVLSKHQD
        70         80         90        100        110        120
VFNQPTLNSF MGLGQAAWKE ARVFLQNLLS VSQARLRDDT ELRKCAFISQ ASATMHLPAT
       130        140        150        160        170        180
IGDYTDFYSS RQHATNVGIM FRDKENALMP NWLHLPVGYH GRASSVVVSG TPIRRPMGQM
       190        200        210        220        230        240
KPDDSKPPVY GACKLLDMEL EMAFFVGPGN RLGEPIPISK AHEHIFGMVL MNDWSARDIQ
       250        260        270        280        290        300
KWEYVPLGPF LGKSFGTTVS PWVVPMDALM PFAVPNPKQD PRPLPYLCHD EPYTFDINLS
       310        320        330        340        350        360
VNLKGEGMSQ AATICKSNFK YMYWTMLQQL THHSVNGCNL RPGDLLASGT ISGPEPENFG
       370        380        390        400        410
SMLELSWKGT KPIDLGNGQT RKFLLDGDEV IITGYCQGDG YRIGFGQCAG KVLPALLPS

Isoforms

- Isoform 2 of Fumarylacetoacetase

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P16930-2-unknown	MSFIPV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P16930-2-Acetylation	SFIPVA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P16930-2-Acetylation	SFIPVA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P16930-2-Acetylation	SFIPVA...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P16930-2-Acetylation	SFIPVA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P16930-71-unknown	MGLGQA...	71		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000454271

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...VGYHGR	161	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000453152
...ALLPS	419	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...ALLPS	419		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ALLPS	419		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)