TopFIND 4.0

P17178: Sterol 26-hydroxylase, mitochondrial {ECO:0000303|PubMed:2175615}

General Information

Protein names
- Sterol 26-hydroxylase, mitochondrial {ECO:0000303|PubMed:2175615}
- 1.14.15.15 {ECO:0000250|UniProtKB:P17177, ECO:0000250|UniProtKB:Q02318}
- 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase
- Cytochrome P-450C27/25
- Cytochrome P450 27
- Sterol 27-hydroxylase {ECO:0000250|UniProtKB:Q02318}
- Vitamin D(3) 25-hydroxylase {ECO:0000303|PubMed:2175615}
Gene names Cyp27a1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P17178

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAVLSRMRLR WALLDTRVMG HGLCPQGARA KAAIPAALRD HESTEGPGTG QDRPRLRSLA 
        70         80         90        100        110        120 
ELPGPGTLRF LFQLFLRGYV LHLHELQALN KAKYGPMWTT TFGTRTNVNL ASAPLLEQVM 
       130        140        150        160        170        180 
RQEGKYPIRD SMEQWKEHRD HKGLSYGIFI TQGQQWYHLR HSLNQRMLKP AEAALYTDAL 
       190        200        210        220        230        240 
NEVISDFIAR LDQVRTESAS GDQVPDVAHL LYHLALEAIC YILFEKRVGC LEPSIPEDTA 
       250        260        270        280        290        300 
TFIRSVGLMF KNSVYVTFLP KWSRPLLPFW KRYMNNWDNI FSFGEKMIHQ KVQEIEAQLQ 
       310        320        330        340        350        360 
AAGPDGVQVS GYLHFLLTKE LLSPQETVGT FPELILAGVD TTSNTLTWAL YHLSKNPEIQ 
       370        380        390        400        410        420 
EALHKEVTGV VPFGKVPQNK DFAHMPLLKA VIKETLRLYP VVPTNSRIIT EKETEINGFL 
       430        440        450        460        470        480 
FPKNTQFVLC HYVVSRDPSV FPEPESFQPH RWLRKREDDN SGIQHPFGSV PFGYGVRSCL 
       490        500        510        520        530    
GRRIAELEMQ LLLSRLIQKY EVVLSPGMGE VKSVSRIVLV PSKKVSLRFL QRQ

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P17178-33-unknown AIPAAL... 33 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...FLQRQ 533 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)