TopFIND 4.0

P17425: Hydroxymethylglutaryl-CoA synthase, cytoplasmic {ECO:0000305}

General Information

Protein names
- Hydroxymethylglutaryl-CoA synthase, cytoplasmic {ECO:0000305}
- HMG-CoA synthase {ECO:0000250|UniProtKB:Q01581}
- 2.3.3.10
- 3-hydroxy-3-methylglutaryl coenzyme A synthase
Gene names Hmgcs1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P17425

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPGSLPLNAE ACWPKDVGIV ALEIYFPSQY VDQAELEKYD GVDAGKYTIG LGQARMGFCT 
        70         80         90        100        110        120 
DREDINSLCL TVVQKLMERN SLSYDCIGRL EVGTETIIDK SKSVKSNLMQ LFEESGNTDI 
       130        140        150        160        170        180 
EGIDTTNACY GGTAAVFNAV NWIESSSWDG RYALVVAGDI AIYASGNARP TGGVGAVALL 
       190        200        210        220        230        240 
IGPNAPVIFD RGLRGTHMQH AYDFYKPDML SEYPVVDGKL SIQCYLSALD RCYSVYRKKI 
       250        260        270        280        290        300 
RAQWQKEGKD KDFTLNDFGF MIFHSPYCKL VQKSLARMFL NDFLNDQNRD KNSIYSGLEA 
       310        320        330        340        350        360 
FGDVKLEDTY FDRDVEKAFM KASAELFNQK TKASLLVSNQ NGNMYTSSVY GSLASVLAQY 
       370        380        390        400        410        420 
SPQQLAGKRI GVFSYGSGLA ATLYSLKVTQ DATPGSALDK ITASLCDLKS RLDSRTCVAP 
       430        440        450        460        470        480 
DVFAENMKLR EDTHHLANYI PQCSIDSLFE GTWYLVRVDE KHRRTYARRP STNDHSLDEG 
       490        500        510        520    
VGLVHSNTAT EHIPSPAKKV PRLPATSGEP ESAVISNGEH 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P17425-1-unknown MPGSLP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SNGEH 520 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)