TopFIND 4.0

P18510: Interleukin-1 receptor antagonist protein

General Information

Protein names
- Interleukin-1 receptor antagonist protein
- IL-1RN
- IL-1ra
- IRAP
- ICIL-1RA
- IL1 inhibitor
- Anakinra
Gene names IL1RN
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P18510

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEICRGLRSH LITLLLFLFH SETICRPSGR KSSKMQAFRI WDVNQKTFYL RNNQLVAGYL 
        70         80         90        100        110        120 
QGPNVNLEEK IDVVPIEPHA LFLGIHGGKM CLSCVKSGDE TRLQLEAVNI TDLSENRKQD 
       130        140        150        160        170    
KRFAFIRSDS GPTTSFESAA CPGWFLCTAM EADQPVSLTN MPDEGVMVTK FYFQEDE

Isoforms

- Isoform 2 of Interleukin-1 receptor antagonist protein - Isoform 3 of Interleukin-1 receptor antagonist protein - Isoform 4 of Interleukin-1 receptor antagonist protein

Sequence View

        10         20         30         40         50         60 
MEICRGLRSH LITLLLFLFH SETICRPSGR KSSKMQAFRI WDVNQKTFYL RNNQLVAGYL 
        70         80         90        100        110        120 
QGPNVNLEEK IDVVPIEPHA LFLGIHGGKM CLSCVKSGDE TRLQLEAVNI TDLSENRKQD 
       130        140        150        160        170    
KRFAFIRSDS GPTTSFESAA CPGWFLCTAM EADQPVSLTN MPDEGVMVTK FYFQEDE         10         20         30         40         50         60 
MEICRGLRSH LITLLLFLFH SETICRPSGR KSSKMQAFRI WDVNQKTFYL RNNQLVAGYL 
        70         80         90        100        110        120 
QGPNVNLEEK IDVVPIEPHA LFLGIHGGKM CLSCVKSGDE TRLQLEAVNI TDLSENRKQD 
       130        140        150        160        170    
KRFAFIRSDS GPTTSFESAA CPGWFLCTAM EADQPVSLTN MPDEGVMVTK FYFQEDE         10         20         30         40         50         60 
MEICRGLRSH LITLLLFLFH SETICRPSGR KSSKMQAFRI WDVNQKTFYL RNNQLVAGYL 
        70         80         90        100        110        120 
QGPNVNLEEK IDVVPIEPHA LFLGIHGGKM CLSCVKSGDE TRLQLEAVNI TDLSENRKQD 
       130        140        150        160        170    
KRFAFIRSDS GPTTSFESAA CPGWFLCTAM EADQPVSLTN MPDEGVMVTK FYFQEDE



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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)