TopFIND 4.0

P19484: Transcription factor EB

General Information

Protein names
- Transcription factor EB
- Class E basic helix-loop-helix protein 35
- bHLHe35
Gene names TFEB
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P19484

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASRIGLRMQ LMREQAQQEE QRERMQQQAV MHYMQQQQQQ QQQQLGGPPT PAINTPVHFQ 
        70         80         90        100        110        120 
SPPPVPGEVL KVQSYLENPT SYHLQQSQHQ KVREYLSETY GNKFAAHISP AQGSPKPPPA 
       130        140        150        160        170        180 
ASPGVRAGHV LSSSAGNSAP NSPMAMLHIG SNPERELDDV IDNIMRLDDV LGYINPEMQM 
       190        200        210        220        230        240 
PNTLPLSSSH LNVYSSDPQV TASLVGVTSS SCPADLTQKR ELTDAESRAL AKERQKKDNH 
       250        260        270        280        290        300 
NLIERRRRFN INDRIKELGM LIPKANDLDV RWNKGTILKA SVDYIRRMQK DLQKSRELEN 
       310        320        330        340        350        360 
HSRRLEMTNK QLWLRIQELE MQARVHGLPT TSPSGMNMAE LAQQVVKQEL PSEEGPGEAL 
       370        380        390        400        410        420 
MLGAEVPDPE PLPALPPQAP LPLPTQPPSP FHHLDFSHSL SFGGREDEGP PGYPEPLAPG 
       430        440        450        460        470    
HGSPFPSLSK KDLDLMLLDD SLLPLASDPL LSTMSPEASK ASSRRSSFSM EEGDVL

Isoforms

- Isoform 2 of Transcription factor EB

Sequence View

        10         20         30         40         50         60 
MASRIGLRMQ LMREQAQQEE QRERMQQQAV MHYMQQQQQQ QQQQLGGPPT PAINTPVHFQ 
        70         80         90        100        110        120 
SPPPVPGEVL KVQSYLENPT SYHLQQSQHQ KVREYLSETY GNKFAAHISP AQGSPKPPPA 
       130        140        150        160        170        180 
ASPGVRAGHV LSSSAGNSAP NSPMAMLHIG SNPERELDDV IDNIMRLDDV LGYINPEMQM 
       190        200        210        220        230        240 
PNTLPLSSSH LNVYSSDPQV TASLVGVTSS SCPADLTQKR ELTDAESRAL AKERQKKDNH 
       250        260        270        280        290        300 
NLIERRRRFN INDRIKELGM LIPKANDLDV RWNKGTILKA SVDYIRRMQK DLQKSRELEN 
       310        320        330        340        350        360 
HSRRLEMTNK QLWLRIQELE MQARVHGLPT TSPSGMNMAE LAQQVVKQEL PSEEGPGEAL 
       370        380        390        400        410        420 
MLGAEVPDPE PLPALPPQAP LPLPTQPPSP FHHLDFSHSL SFGGREDEGP PGYPEPLAPG 
       430        440        450        460        470    
HGSPFPSLSK KDLDLMLLDD SLLPLASDPL LSTMSPEASK ASSRRSSFSM EEGDVL



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P19484-1-unknown MASRIG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P19484-1-unknown MASRIG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91997
    P19484-74- SYLENP... 74 Subtiligase Based Positive Selection Wells DB_Untreated 23264352

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EGDVL 476 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EGDVL 476 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87615

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)