P19544: Wilms tumor protein

General Information

Protein names	- Wilms tumor protein - WT33
Gene names	WT1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P19544

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Wilms tumor protein - Isoform 3 of Wilms tumor protein - Isoform 4 of Wilms tumor protein - Isoform 6 of Wilms tumor protein - Isoform 7 of Wilms tumor protein - Isoform 8 of Wilms tumor protein - Isoform 9 of Wilms tumor protein

Sequence View

        10         20         30         40         50         60
MGSDVRDLNA LLPAVPSLGG GGGCALPVSG AAQWAPVLDF APPGASAYGS LGGPAPPPAP
        70         80         90        100        110        120
PPPPPPPPHS FIKQEPSWGG AEPHEEQCLS AFTVHFSGQF TGTAGACRYG PFGPPPPSQA
       130        140        150        160        170        180
SSGQARMFPN APYLPSCLES QPAIRNQGYS TVTFDGTPSY GHTPSHHAAQ FPNHSFKHED
       190        200        210        220        230        240
PMGQQGSLGE QQYSVPPPVY GCHTPTDSCT GSQALLLRTP YSSDNLYQMT SQLECMTWNQ
       250        260        270        280        290        300
MNLGATLKGV AAGSSSSVKW TEGQSNHSTG YESDNHTTPI LCGAQYRIHT HGVFRGIQDV
       310        320        330        340        350        360
RRVPGVAPTL VRSASETSEK RPFMCAYPGC NKRYFKLSHL QMHSRKHTGE KPYQCDFKDC
       370        380        390        400        410        420
ERRFSRSDQL KRHQRRHTGV KPFQCKTCQR KFSRSDHLKT HTRTHTGKTS EKPFSCRWPS
       430        440
CQKKFARSDE LVRHHNMHQR NMTKLQLAL         10         20         30         40         50         60
MGSDVRDLNA LLPAVPSLGG GGGCALPVSG AAQWAPVLDF APPGASAYGS LGGPAPPPAP
        70         80         90        100        110        120
PPPPPPPPHS FIKQEPSWGG AEPHEEQCLS AFTVHFSGQF TGTAGACRYG PFGPPPPSQA
       130        140        150        160        170        180
SSGQARMFPN APYLPSCLES QPAIRNQGYS TVTFDGTPSY GHTPSHHAAQ FPNHSFKHED
       190        200        210        220        230        240
PMGQQGSLGE QQYSVPPPVY GCHTPTDSCT GSQALLLRTP YSSDNLYQMT SQLECMTWNQ
       250        260        270        280        290        300
MNLGATLKGV AAGSSSSVKW TEGQSNHSTG YESDNHTTPI LCGAQYRIHT HGVFRGIQDV
       310        320        330        340        350        360
RRVPGVAPTL VRSASETSEK RPFMCAYPGC NKRYFKLSHL QMHSRKHTGE KPYQCDFKDC
       370        380        390        400        410        420
ERRFSRSDQL KRHQRRHTGV KPFQCKTCQR KFSRSDHLKT HTRTHTGKTS EKPFSCRWPS
       430        440
CQKKFARSDE LVRHHNMHQR NMTKLQLAL         10         20         30         40         50         60
MGSDVRDLNA LLPAVPSLGG GGGCALPVSG AAQWAPVLDF APPGASAYGS LGGPAPPPAP
        70         80         90        100        110        120
PPPPPPPPHS FIKQEPSWGG AEPHEEQCLS AFTVHFSGQF TGTAGACRYG PFGPPPPSQA
       130        140        150        160        170        180
SSGQARMFPN APYLPSCLES QPAIRNQGYS TVTFDGTPSY GHTPSHHAAQ FPNHSFKHED
       190        200        210        220        230        240
PMGQQGSLGE QQYSVPPPVY GCHTPTDSCT GSQALLLRTP YSSDNLYQMT SQLECMTWNQ
       250        260        270        280        290        300
MNLGATLKGV AAGSSSSVKW TEGQSNHSTG YESDNHTTPI LCGAQYRIHT HGVFRGIQDV
       310        320        330        340        350        360
RRVPGVAPTL VRSASETSEK RPFMCAYPGC NKRYFKLSHL QMHSRKHTGE KPYQCDFKDC
       370        380        390        400        410        420
ERRFSRSDQL KRHQRRHTGV KPFQCKTCQR KFSRSDHLKT HTRTHTGKTS EKPFSCRWPS
       430        440
CQKKFARSDE LVRHHNMHQR NMTKLQLAL         10         20         30         40         50         60
MGSDVRDLNA LLPAVPSLGG GGGCALPVSG AAQWAPVLDF APPGASAYGS LGGPAPPPAP
        70         80         90        100        110        120
PPPPPPPPHS FIKQEPSWGG AEPHEEQCLS AFTVHFSGQF TGTAGACRYG PFGPPPPSQA
       130        140        150        160        170        180
SSGQARMFPN APYLPSCLES QPAIRNQGYS TVTFDGTPSY GHTPSHHAAQ FPNHSFKHED
       190        200        210        220        230        240
PMGQQGSLGE QQYSVPPPVY GCHTPTDSCT GSQALLLRTP YSSDNLYQMT SQLECMTWNQ
       250        260        270        280        290        300
MNLGATLKGV AAGSSSSVKW TEGQSNHSTG YESDNHTTPI LCGAQYRIHT HGVFRGIQDV
       310        320        330        340        350        360
RRVPGVAPTL VRSASETSEK RPFMCAYPGC NKRYFKLSHL QMHSRKHTGE KPYQCDFKDC
       370        380        390        400        410        420
ERRFSRSDQL KRHQRRHTGV KPFQCKTCQR KFSRSDHLKT HTRTHTGKTS EKPFSCRWPS
       430        440
CQKKFARSDE LVRHHNMHQR NMTKLQLAL         10         20         30         40         50         60
MGSDVRDLNA LLPAVPSLGG GGGCALPVSG AAQWAPVLDF APPGASAYGS LGGPAPPPAP
        70         80         90        100        110        120
PPPPPPPPHS FIKQEPSWGG AEPHEEQCLS AFTVHFSGQF TGTAGACRYG PFGPPPPSQA
       130        140        150        160        170        180
SSGQARMFPN APYLPSCLES QPAIRNQGYS TVTFDGTPSY GHTPSHHAAQ FPNHSFKHED
       190        200        210        220        230        240
PMGQQGSLGE QQYSVPPPVY GCHTPTDSCT GSQALLLRTP YSSDNLYQMT SQLECMTWNQ
       250        260        270        280        290        300
MNLGATLKGV AAGSSSSVKW TEGQSNHSTG YESDNHTTPI LCGAQYRIHT HGVFRGIQDV
       310        320        330        340        350        360
RRVPGVAPTL VRSASETSEK RPFMCAYPGC NKRYFKLSHL QMHSRKHTGE KPYQCDFKDC
       370        380        390        400        410        420
ERRFSRSDQL KRHQRRHTGV KPFQCKTCQR KFSRSDHLKT HTRTHTGKTS EKPFSCRWPS
       430        440
CQKKFARSDE LVRHHNMHQR NMTKLQLAL         10         20         30         40         50         60
MGSDVRDLNA LLPAVPSLGG GGGCALPVSG AAQWAPVLDF APPGASAYGS LGGPAPPPAP
        70         80         90        100        110        120
PPPPPPPPHS FIKQEPSWGG AEPHEEQCLS AFTVHFSGQF TGTAGACRYG PFGPPPPSQA
       130        140        150        160        170        180
SSGQARMFPN APYLPSCLES QPAIRNQGYS TVTFDGTPSY GHTPSHHAAQ FPNHSFKHED
       190        200        210        220        230        240
PMGQQGSLGE QQYSVPPPVY GCHTPTDSCT GSQALLLRTP YSSDNLYQMT SQLECMTWNQ
       250        260        270        280        290        300
MNLGATLKGV AAGSSSSVKW TEGQSNHSTG YESDNHTTPI LCGAQYRIHT HGVFRGIQDV
       310        320        330        340        350        360
RRVPGVAPTL VRSASETSEK RPFMCAYPGC NKRYFKLSHL QMHSRKHTGE KPYQCDFKDC
       370        380        390        400        410        420
ERRFSRSDQL KRHQRRHTGV KPFQCKTCQR KFSRSDHLKT HTRTHTGKTS EKPFSCRWPS
       430        440
CQKKFARSDE LVRHHNMHQR NMTKLQLAL         10         20         30         40         50         60
MGSDVRDLNA LLPAVPSLGG GGGCALPVSG AAQWAPVLDF APPGASAYGS LGGPAPPPAP
        70         80         90        100        110        120
PPPPPPPPHS FIKQEPSWGG AEPHEEQCLS AFTVHFSGQF TGTAGACRYG PFGPPPPSQA
       130        140        150        160        170        180
SSGQARMFPN APYLPSCLES QPAIRNQGYS TVTFDGTPSY GHTPSHHAAQ FPNHSFKHED
       190        200        210        220        230        240
PMGQQGSLGE QQYSVPPPVY GCHTPTDSCT GSQALLLRTP YSSDNLYQMT SQLECMTWNQ
       250        260        270        280        290        300
MNLGATLKGV AAGSSSSVKW TEGQSNHSTG YESDNHTTPI LCGAQYRIHT HGVFRGIQDV
       310        320        330        340        350        360
RRVPGVAPTL VRSASETSEK RPFMCAYPGC NKRYFKLSHL QMHSRKHTGE KPYQCDFKDC
       370        380        390        400        410        420
ERRFSRSDQL KRHQRRHTGV KPFQCKTCQR KFSRSDHLKT HTRTHTGKTS EKPFSCRWPS
       430        440
CQKKFARSDE LVRHHNMHQR NMTKLQLAL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P19544-1-unknown	MGSDVR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P19544-1-unknown	MGSDVR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt94644
P19544-1-unknown	MGSDVR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt94645
P19544-1-unknown	MGSDVR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt94646
P19544-1-unknown	MGSDVR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100123
P19544-1-unknown	MGSDVR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100124

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...LQLAL	449	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LQLAL	449	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90268
...LQLAL	449	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90265
...LQLAL	449	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90262
...LQLAL	449	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90263
...LQLAL	449	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90264
...LQLAL	449	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90267
...LQLAL	449	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90266
...LQLAL	449		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)