TopFIND 4.0

P19812: E3 ubiquitin-protein ligase UBR1

General Information

Protein names
- E3 ubiquitin-protein ligase UBR1
- 2.3.2.27
- N-end-recognizing protein
- N-recognin-1
- RING-type E3 ubiquitin transferase UBR1
Gene names UBR1
Organism Saccharomyces cerevisiae
Protease Family
Protease ID
Chromosome location
UniProt ID P19812

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSVADDDLGS LQGHIRRTLR SIHNLPYFRY TRGPTERADM SRALKEFIYR YLYFVISNSG 
        70         80         90        100        110        120 
ENLPTLFNAH PKQKLSNPEL TVFPDSLEDA VDIDKITSQQ TIPFYKIDES RIGDVHKHTG 
       130        140        150        160        170        180 
RNCGRKFKIG EPLYRCHECG CDDTCVLCIH CFNPKDHVNH HVCTDICTEF TSGICDCGDE 
       190        200        210        220        230        240 
EAWNSPLHCK AEEQENDISE DPATNADIKE EDVWNDSVNI ALVELVLAEV FDYFIDVFNQ 
       250        260        270        280        290        300 
NIEPLPTIQK DITIKLREMT QQGKMYERAQ FLNDLKYEND YMFDGTTTAK TSPSNSPEAS 
       310        320        330        340        350        360 
PSLAKIDPEN YTVIIYNDEY HNYSQATTAL RQGVPDNVHI DLLTSRIDGE GRAMLKCSQD 
       370        380        390        400        410        420 
LSSVLGGFFA VQTNGLSATL TSWSEYLHQE TCKYIILWIT HCLNIPNSSF QTTFRNMMGK 
       430        440        450        460        470        480 
TLCSEYLNAT ECRDMTPVVE KYFSNKFDKN DPYRYIDLSI LADGNQIPLG HHKILPESST 
       490        500        510        520        530        540 
HSLSPLINDV ETPTSRTYSN TRLQHILYFD NRYWKRLRKD IQNVIIPTLA SSNLYKPIFC 
       550        560        570        580        590        600 
QQVVEIFNHI TRSVAYMDRE PQLTAIRECV VQLFTCPTNA KNIFENQSFL DIVWSIIDIF 
       610        620        630        640        650        660 
KEFCKVEGGV LIWQRVQKSN LTKSYSISFK QGLYTVETLL SKVHDPNIPL RPKEIISLLT 
       670        680        690        700        710        720 
LCKLFNGAWK IKRKEGEHVL HEDQNFISYL EYTTSIYSII QTAEKVSEKS KDSIDSKLFL 
       730        740        750        760        770        780 
NAIRIISSFL GNRSLTYKLI YDSHEVIKFS VSHERVAFMN PLQTMLSFLI EKVSLKDAYE 
       790        800        810        820        830        840 
ALEDCSDFLK ISDFSLRSVV LCSQIDVGFW VRNGMSVLHQ ASYYKNNPEL GSYSRDIHLN 
       850        860        870        880        890        900 
QLAILWERDD IPRIIYNILD RWELLDWFTG EVDYQHTVYE DKISFIIQQF IAFIYQILTE 
       910        920        930        940        950        960 
RQYFKTFSSL KDRRMDQIKN SIIYNLYMKP LSYSKLLRSV PDYLTEDTTE FDEALEEVSV 
       970        980        990       1000       1010       1020 
FVEPKGLADN GVFKLKASLY AKVDPLKLLN LENEFESSAT IIKSHLAKDK DEIAKVVLIP 
      1030       1040       1050       1060       1070       1080 
QVSIKQLDKD ALNLGAFTRN TVFAKVVYKL LQVCLDMEDS TFLNELLHLV HGIFRDDELI 
      1090       1100       1110       1120       1130       1140 
NGKDSIPEAY LSKPICNLLL SIANAKSDVF SESIVRKADY LLEKMIMKKP NELFESLIAS 
      1150       1160       1170       1180       1190       1200 
FGNQYVNDYK DKKLRQGVNL QETEKERKRR LAKKHQARLL AKFNNQQTKF MKEHESEFDE 
      1210       1220       1230       1240       1250       1260 
QDNDVDMVGE KVYESEDFTC ALCQDSSSTD FFVIPAYHDH SPIFRPGNIF NPNEFMPMWD 
      1270       1280       1290       1300       1310       1320 
GFYNDDEKQA YIDDDVLEAL KENGSCGSRK VFVSCNHHIH HNCFKRYVQK KRFSSNAFIC 
      1330       1340       1350       1360       1370       1380 
PLCQTFSNCT LPLCQTSKAN TGLSLDMFLE SELSLDTLSR LFKPFTEENY RTINSIFSLM 
      1390       1400       1410       1420       1430       1440 
ISQCQGFDKA VRKRANFSHK DVSLILSVHW ANTISMLEIA SRLEKPYSIS FFRSREQKYK 
      1450       1460       1470       1480       1490       1500 
TLKNILVCIM LFTFVIGKPS MEFEPYPQQP DTVWNQNQLF QYIVRSALFS PVSLRQTVTE 
      1510       1520       1530       1540       1550       1560 
ALTTFSRQFL RDFLQGLSDA EQVTKLYAKA SKIGDVLKVS EQMLFALRTI SDVRMEGLDS 
      1570       1580       1590       1600       1610       1620 
ESIIYDLAYT FLLKSLLPTI RRCLVFIKVL HELVKDSENE TLVINGHEVE EELEFEDTAE 
      1630       1640       1650       1660       1670       1680 
FVNKALKMIT EKESLVDLLT TQESIVSHPY LENIPYEYCG IIKLIDLSKY LNTYVTQSKE 
      1690       1700       1710       1720       1730       1740 
IKLREERSQH MKNADNRLDF KICLTCGVKV HLRADRHEMT KHLNKNCFKP FGAFLMPNSS 
      1750       1760       1770       1780       1790       1800 
EVCLHLTQPP SNIFISAPYL NSHGEVGRNA MRRGDLTTLN LKRYEHLNRL WINNEIPGYI 
      1810       1820       1830       1840       1850       1860 
SRVMGDEFRV TILSNGFLFA FNREPRPRRI PPTDEDDEDM EEGEDGFFTE GNDEMDVDDE 
      1870       1880       1890       1900       1910       1920 
TGQAANLFGV GAEGIAGGGV RDFFQFFENF RNTLQPQGNG DDDAPQNPPP ILQFLGPQFD 
      1930       1940       1950    
GATIIRNTNP RNLDEDDSDD NDDSDEREIW 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P19812-1-unknown MSVADD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EREIW 1950 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)