P19878: Neutrophil cytosol factor 2

General Information

Protein names	- Neutrophil cytosol factor 2 - NCF-2 - 67 kDa neutrophil oxidase factor - NADPH oxidase activator 2 - Neutrophil NADPH oxidase factor 2 - p67-phox
Gene names	NCF2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P19878

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Neutrophil cytosol factor 2 - Isoform 3 of Neutrophil cytosol factor 2 - Isoform 4 of Neutrophil cytosol factor 2

Sequence View

        10         20         30         40         50         60
MSLVEAISLW NEGVLAADKK DWKGALDAFS AVQDPHSRIC FNIGCMYTIL KNMTEAEKAF
        70         80         90        100        110        120
TRSINRDKHL AVAYFQRGML YYQTEKYDLA IKDLKEALIQ LRGNQLIDYK ILGLQFKLFA
       130        140        150        160        170        180
CEVLYNIAFM YAKKEEWKKA EEQLALATSM KSEPRHSKID KAMECVWKQK LYEPVVIPVG
       190        200        210        220        230        240
KLFRPNERQV AQLAKKDYLG KATVVASVVD QDSFSGFAPL QPQAAEPPPR PKTPEIFRAL
       250        260        270        280        290        300
EGEAHRVLFG FVPETKEELQ VMPGNIVFVL KKGNDNWATV MFNGQKGLVP CNYLEPVELR
       310        320        330        340        350        360
IHPQQQPQEE SSPQSDIPAP PSSKAPGRPQ LSPGQKQKEE PKEVKLSVPM PYTLKVHYKY
       370        380        390        400        410        420
TVVMKTQPGL PYSQVRDMVS KKLELRLEHT KLSYRPRDSN ELVPLSEDSM KDAWGQVKNY
       430        440        450        460        470        480
CLTLWCENTV GDQGFPDEPK ESEKADANNQ TTEPQLKKGS QVEALFSYEA TQPEDLEFQE
       490        500        510        520
GDIILVLSKV NEEWLEGECK GKVGIFPKVF VEDCATTDLE STRREV         10         20         30         40         50         60
MSLVEAISLW NEGVLAADKK DWKGALDAFS AVQDPHSRIC FNIGCMYTIL KNMTEAEKAF
        70         80         90        100        110        120
TRSINRDKHL AVAYFQRGML YYQTEKYDLA IKDLKEALIQ LRGNQLIDYK ILGLQFKLFA
       130        140        150        160        170        180
CEVLYNIAFM YAKKEEWKKA EEQLALATSM KSEPRHSKID KAMECVWKQK LYEPVVIPVG
       190        200        210        220        230        240
KLFRPNERQV AQLAKKDYLG KATVVASVVD QDSFSGFAPL QPQAAEPPPR PKTPEIFRAL
       250        260        270        280        290        300
EGEAHRVLFG FVPETKEELQ VMPGNIVFVL KKGNDNWATV MFNGQKGLVP CNYLEPVELR
       310        320        330        340        350        360
IHPQQQPQEE SSPQSDIPAP PSSKAPGRPQ LSPGQKQKEE PKEVKLSVPM PYTLKVHYKY
       370        380        390        400        410        420
TVVMKTQPGL PYSQVRDMVS KKLELRLEHT KLSYRPRDSN ELVPLSEDSM KDAWGQVKNY
       430        440        450        460        470        480
CLTLWCENTV GDQGFPDEPK ESEKADANNQ TTEPQLKKGS QVEALFSYEA TQPEDLEFQE
       490        500        510        520
GDIILVLSKV NEEWLEGECK GKVGIFPKVF VEDCATTDLE STRREV         10         20         30         40         50         60
MSLVEAISLW NEGVLAADKK DWKGALDAFS AVQDPHSRIC FNIGCMYTIL KNMTEAEKAF
        70         80         90        100        110        120
TRSINRDKHL AVAYFQRGML YYQTEKYDLA IKDLKEALIQ LRGNQLIDYK ILGLQFKLFA
       130        140        150        160        170        180
CEVLYNIAFM YAKKEEWKKA EEQLALATSM KSEPRHSKID KAMECVWKQK LYEPVVIPVG
       190        200        210        220        230        240
KLFRPNERQV AQLAKKDYLG KATVVASVVD QDSFSGFAPL QPQAAEPPPR PKTPEIFRAL
       250        260        270        280        290        300
EGEAHRVLFG FVPETKEELQ VMPGNIVFVL KKGNDNWATV MFNGQKGLVP CNYLEPVELR
       310        320        330        340        350        360
IHPQQQPQEE SSPQSDIPAP PSSKAPGRPQ LSPGQKQKEE PKEVKLSVPM PYTLKVHYKY
       370        380        390        400        410        420
TVVMKTQPGL PYSQVRDMVS KKLELRLEHT KLSYRPRDSN ELVPLSEDSM KDAWGQVKNY
       430        440        450        460        470        480
CLTLWCENTV GDQGFPDEPK ESEKADANNQ TTEPQLKKGS QVEALFSYEA TQPEDLEFQE
       490        500        510        520
GDIILVLSKV NEEWLEGECK GKVGIFPKVF VEDCATTDLE STRREV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P19878-1-unknown	MSLVEA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P19878-1-unknown	MSLVEA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82375
P19878-1-unknown	MSLVEA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82376
P19878-1-unknown	MSLVEA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82377
P19878-213-unknown	SFSGFA...	213	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175677
P19878-213-unknown	SFSGFA...	213	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175679
P19878-213-unknown	SFSGFA...	213	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175678
P19878-213-	SFSGFA...	213		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GECKGK	501	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77993
...GECKGK	501	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92721
...GECKGK	501	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92722
...TRREV	526	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TRREV	526	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77995
...TRREV	526	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77994

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)