TopFIND 4.0

P20062: Transcobalamin-2

General Information

Protein names
- Transcobalamin-2
- TC-2
- Transcobalamin II
- TC II
- TCII
Gene names TCN2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P20062

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRHLGAFLFL LGVLGALTEM CEIPEMDSHL VEKLGQHLLP WMDRLSLEHL NPSIYVGLRL 
        70         80         90        100        110        120 
SSLQAGTKED LYLHSLKLGY QQCLLGSAFS EDDGDCQGKP SMGQLALYLL ALRANCEFVR 
       130        140        150        160        170        180 
GHKGDRLVSQ LKWFLEDEKR AIGHDHKGHP HTSYYQYGLG ILALCLHQKR VHDSVVDKLL 
       190        200        210        220        230        240 
YAVEPFHQGH HSVDTAAMAG LAFTCLKRSN FNPGRRQRIT MAIRTVREEI LKAQTPEGHF 
       250        260        270        280        290        300 
GNVYSTPLAL QFLMTSPMRG AELGTACLKA RVALLASLQD GAFQNALMIS QLLPVLNHKT 
       310        320        330        340        350        360 
YIDLIFPDCL APRVMLEPAA ETIPQTQEII SVTLQVLSLL PPYRQSISVL AGSTVEDVLK 
       370        380        390        400        410        420 
KAHELGGFTY ETQASLSGPY LTSVMGKAAG EREFWQLLRD PNTPLLQGIA DYRPKDGETI 
   
ELRLVSW

Isoforms

- Isoform 2 of Transcobalamin-2

Sequence View

        10         20         30         40         50         60 
MRHLGAFLFL LGVLGALTEM CEIPEMDSHL VEKLGQHLLP WMDRLSLEHL NPSIYVGLRL 
        70         80         90        100        110        120 
SSLQAGTKED LYLHSLKLGY QQCLLGSAFS EDDGDCQGKP SMGQLALYLL ALRANCEFVR 
       130        140        150        160        170        180 
GHKGDRLVSQ LKWFLEDEKR AIGHDHKGHP HTSYYQYGLG ILALCLHQKR VHDSVVDKLL 
       190        200        210        220        230        240 
YAVEPFHQGH HSVDTAAMAG LAFTCLKRSN FNPGRRQRIT MAIRTVREEI LKAQTPEGHF 
       250        260        270        280        290        300 
GNVYSTPLAL QFLMTSPMRG AELGTACLKA RVALLASLQD GAFQNALMIS QLLPVLNHKT 
       310        320        330        340        350        360 
YIDLIFPDCL APRVMLEPAA ETIPQTQEII SVTLQVLSLL PPYRQSISVL AGSTVEDVLK 
       370        380        390        400        410        420 
KAHELGGFTY ETQASLSGPY LTSVMGKAAG EREFWQLLRD PNTPLLQGIA DYRPKDGETI 
   
ELRLVSW



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P20062-1-unknown MRHLGA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91731
    P20062-19-unknown EMCEIP... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P20062-19-unknown EMCEIP... 19 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112111

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RLVSW 427 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RLVSW 427 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87349

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)