TopFIND 4.0

P20809: Interleukin-11

General Information

Protein names
- Interleukin-11
- IL-11
- Adipogenesis inhibitory factor {ECO:0000303|PubMed:1828438}
- AGIF {ECO:0000303|PubMed:1828438}
- Oprelvekin
Gene names IL11
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P20809

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNCVCRLVLV VLSLWPDTAV APGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL 
        70         80         90        100        110        120 
RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK 
       130        140        150        160        170        180 
TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG 
       190    
LHLTLDWAVR GLLLLKTRL

Isoforms

- Isoform 2 of Interleukin-11

Sequence View

        10         20         30         40         50         60 
MNCVCRLVLV VLSLWPDTAV APGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL 
        70         80         90        100        110        120 
RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK 
       130        140        150        160        170        180 
TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG 
       190    
LHLTLDWAVR GLLLLKTRL



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Evidence Codes:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P20809-22-unknown PGPPPG... 22 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P20809-80-unknown MSAGAL... 80 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77723

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LKTRL 199 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LKTRL 199 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73341

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)