TopFIND 4.0

P20815: Cytochrome P450 3A5

General Information

Protein names
- Cytochrome P450 3A5
- 1.14.14.1
- CYPIIIA5
- Cytochrome P450 HLp2
- Cytochrome P450-PCN3
Gene names CYP3A5
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P20815

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLIPNLAVE TWLLLAVSLV LLYLYGTRTH GLFKRLGIPG PTPLPLLGNV LSYRQGLWKF 
        70         80         90        100        110        120 
DTECYKKYGK MWGTYEGQLP VLAITDPDVI RTVLVKECYS VFTNRRSLGP VGFMKSAISL 
       130        140        150        160        170        180 
AEDEEWKRIR SLLSPTFTSG KLKEMFPIIA QYGDVLVRNL RREAEKGKPV TLKDIFGAYS 
       190        200        210        220        230        240 
MDVITGTSFG VNIDSLNNPQ DPFVESTKKF LKFGFLDPLF LSIILFPFLT PVFEALNVSL 
       250        260        270        280        290        300 
FPKDTINFLS KSVNRMKKSR LNDKQKHRLD FLQLMIDSQN SKETESHKAL SDLELAAQSI 
       310        320        330        340        350        360 
IFIFAGYETT SSVLSFTLYE LATHPDVQQK LQKEIDAVLP NKAPPTYDAV VQMEYLDMVV 
       370        380        390        400        410        420 
NETLRLFPVA IRLERTCKKD VEINGVFIPK GSMVVIPTYA LHHDPKYWTE PEEFRPERFS 
       430        440        450        460        470        480 
KKKDSIDPYI YTPFGTGPRN CIGMRFALMN MKLALIRVLQ NFSFKPCKET QIPLKLDTQG 
       490        500    
LLQPEKPIVL KVDSRDGTLS GE

Isoforms

- Isoform 2 of Cytochrome P450 3A5

Sequence View

        10         20         30         40         50         60 
MDLIPNLAVE TWLLLAVSLV LLYLYGTRTH GLFKRLGIPG PTPLPLLGNV LSYRQGLWKF 
        70         80         90        100        110        120 
DTECYKKYGK MWGTYEGQLP VLAITDPDVI RTVLVKECYS VFTNRRSLGP VGFMKSAISL 
       130        140        150        160        170        180 
AEDEEWKRIR SLLSPTFTSG KLKEMFPIIA QYGDVLVRNL RREAEKGKPV TLKDIFGAYS 
       190        200        210        220        230        240 
MDVITGTSFG VNIDSLNNPQ DPFVESTKKF LKFGFLDPLF LSIILFPFLT PVFEALNVSL 
       250        260        270        280        290        300 
FPKDTINFLS KSVNRMKKSR LNDKQKHRLD FLQLMIDSQN SKETESHKAL SDLELAAQSI 
       310        320        330        340        350        360 
IFIFAGYETT SSVLSFTLYE LATHPDVQQK LQKEIDAVLP NKAPPTYDAV VQMEYLDMVV 
       370        380        390        400        410        420 
NETLRLFPVA IRLERTCKKD VEINGVFIPK GSMVVIPTYA LHHDPKYWTE PEEFRPERFS 
       430        440        450        460        470        480 
KKKDSIDPYI YTPFGTGPRN CIGMRFALMN MKLALIRVLQ NFSFKPCKET QIPLKLDTQG 
       490        500    
LLQPEKPIVL KVDSRDGTLS GE



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P20815-1-unknown MDLIPN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P20815-1-unknown MDLIPN... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71526

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TLSGE 502 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)