TopFIND 4.0

P21237: Brain-derived neurotrophic factor {ECO:0000303|PubMed:2369898}

General Information

Protein names
- Brain-derived neurotrophic factor {ECO:0000303|PubMed:2369898}
- BDNF {ECO:0000303|PubMed:2369898}
- BDNF precursor form {ECO:0000305}
- ProBDNF {ECO:0000305}
Gene names Bdnf
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P21237

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTILFLTMVI SYFGCMKAAP MKEVNVHGQG NLAYPGVRTH GTLESVNGPR AGSRGLTTTS 
        70         80         90        100        110        120 
LADTFEHVIE ELLDEDQKVR PNEENHKDAD LYTSRVMLSS QVPLEPPLLF LLEEYKNYLD 
       130        140        150        160        170        180 
AANMSMRVRR HSDPARRGEL SVCDSISEWV TAADKKTAVD MSGGTVTVLE KVPVSKGQLK 
       190        200        210        220        230        240 
QYFYETKCNP MGYTKEGCRG IDKRHWNSQC RTTQSYVRAL TMDSKKRIGW RFIRIDTSCV 
   
CTLTIKRGR

Isoforms

- Isoform 2 of Brain-derived neurotrophic factor

Sequence View

        10         20         30         40         50         60 
MTILFLTMVI SYFGCMKAAP MKEVNVHGQG NLAYPGVRTH GTLESVNGPR AGSRGLTTTS 
        70         80         90        100        110        120 
LADTFEHVIE ELLDEDQKVR PNEENHKDAD LYTSRVMLSS QVPLEPPLLF LLEEYKNYLD 
       130        140        150        160        170        180 
AANMSMRVRR HSDPARRGEL SVCDSISEWV TAADKKTAVD MSGGTVTVLE KVPVSKGQLK 
       190        200        210        220        230        240 
QYFYETKCNP MGYTKEGCRG IDKRHWNSQC RTTQSYVRAL TMDSKKRIGW RFIRIDTSCV 
   
CTLTIKRGR



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P21237-19-unknown APMKEV... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P21237-131-unknown HSDPAR... 131 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IKRGR 249 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)