TopFIND 4.0

P22309: UDP-glucuronosyltransferase 1-1

General Information

Protein names
- UDP-glucuronosyltransferase 1-1
- UDPGT 1-1
- UGT1*1
- UGT1-01
- UGT1.1
- 2.4.1.17
- Bilirubin-specific UDPGT isozyme 1
- hUG-BR1
- UDP-glucuronosyltransferase 1-A
- UGT-1A
- UGT1A
- UDP-glucuronosyltransferase 1A1
Gene names UGT1A1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P22309

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAVESQGGRP LVLGLLLCVL GPVVSHAGKI LLIPVDGSHW LSMLGAIQQL QQRGHEIVVL 
        70         80         90        100        110        120 
APDASLYIRD GAFYTLKTYP VPFQREDVKE SFVSLGHNVF ENDSFLQRVI KTYKKIKKDS 
       130        140        150        160        170        180 
AMLLSGCSHL LHNKELMASL AESSFDVMLT DPFLPCSPIV AQYLSLPTVF FLHALPCSLE 
       190        200        210        220        230        240 
FEATQCPNPF SYVPRPLSSH SDHMTFLQRV KNMLIAFSQN FLCDVVYSPY ATLASEFLQR 
       250        260        270        280        290        300 
EVTVQDLLSS ASVWLFRSDF VKDYPRPIMP NMVFVGGINC LHQNPLSQEF EAYINASGEH 
       310        320        330        340        350        360 
GIVVFSLGSM VSEIPEKKAM AIADALGKIP QTVLWRYTGT RPSNLANNTI LVKWLPQNDL 
       370        380        390        400        410        420 
LGHPMTRAFI THAGSHGVYE SICNGVPMVM MPLFGDQMDN AKRMETKGAG VTLNVLEMTS 
       430        440        450        460        470        480 
EDLENALKAV INDKSYKENI MRLSSLHKDR PVEPLDLAVF WVEFVMRHKG APHLRPAAHD 
       490        500        510        520        530    
LTWYQYHSLD VIGFLLAVVL TVAFITFKCC AYGYRKCLGK KGRVKKAHKS KTH

Isoforms

- Isoform 2 of UDP-glucuronosyltransferase 1-1

Sequence View

        10         20         30         40         50         60 
MAVESQGGRP LVLGLLLCVL GPVVSHAGKI LLIPVDGSHW LSMLGAIQQL QQRGHEIVVL 
        70         80         90        100        110        120 
APDASLYIRD GAFYTLKTYP VPFQREDVKE SFVSLGHNVF ENDSFLQRVI KTYKKIKKDS 
       130        140        150        160        170        180 
AMLLSGCSHL LHNKELMASL AESSFDVMLT DPFLPCSPIV AQYLSLPTVF FLHALPCSLE 
       190        200        210        220        230        240 
FEATQCPNPF SYVPRPLSSH SDHMTFLQRV KNMLIAFSQN FLCDVVYSPY ATLASEFLQR 
       250        260        270        280        290        300 
EVTVQDLLSS ASVWLFRSDF VKDYPRPIMP NMVFVGGINC LHQNPLSQEF EAYINASGEH 
       310        320        330        340        350        360 
GIVVFSLGSM VSEIPEKKAM AIADALGKIP QTVLWRYTGT RPSNLANNTI LVKWLPQNDL 
       370        380        390        400        410        420 
LGHPMTRAFI THAGSHGVYE SICNGVPMVM MPLFGDQMDN AKRMETKGAG VTLNVLEMTS 
       430        440        450        460        470        480 
EDLENALKAV INDKSYKENI MRLSSLHKDR PVEPLDLAVF WVEFVMRHKG APHLRPAAHD 
       490        500        510        520        530    
LTWYQYHSLD VIGFLLAVVL TVAFITFKCC AYGYRKCLGK KGRVKKAHKS KTH



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P22309-1-unknown MAVESQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93808
    P22309-26-unknown HAGKIL... 26 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P22309-26-unknown HAGKIL... 26 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt114118

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KSKTH 533 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)