TopFIND 4.0

P22310: UDP-glucuronosyltransferase 1-4

General Information

Protein names
- UDP-glucuronosyltransferase 1-4
- UDPGT 1-4
- UGT1*4
- UGT1-04
- UGT1.4
- 2.4.1.17
- Bilirubin-specific UDPGT isozyme 2
- hUG-BR2
- UDP-glucuronosyltransferase 1-D
- UGT-1D
- UGT1D
- UDP-glucuronosyltransferase 1A4
Gene names UGT1A4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P22310

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MARGLQVPLP RLATGLLLLL SVQPWAESGK VLVVPTDGSP WLSMREALRE LHARGHQAVV 
        70         80         90        100        110        120 
LTPEVNMHIK EEKFFTLTAY AVPWTQKEFD RVTLGYTQGF FETEHLLKRY SRSMAIMNNV 
       130        140        150        160        170        180 
SLALHRCCVE LLHNEALIRH LNATSFDVVL TDPVNLCGAV LAKYLSIPAV FFWRYIPCDL 
       190        200        210        220        230        240 
DFKGTQCPNP SSYIPKLLTT NSDHMTFLQR VKNMLYPLAL SYICHTFSAP YASLASELFQ 
       250        260        270        280        290        300 
REVSVVDLVS YASVWLFRGD FVMDYPRPIM PNMVFIGGIN CANGKPLSQE FEAYINASGE 
       310        320        330        340        350        360 
HGIVVFSLGS MVSEIPEKKA MAIADALGKI PQTVLWRYTG TRPSNLANNT ILVKWLPQND 
       370        380        390        400        410        420 
LLGHPMTRAF ITHAGSHGVY ESICNGVPMV MMPLFGDQMD NAKRMETKGA GVTLNVLEMT 
       430        440        450        460        470        480 
SEDLENALKA VINDKSYKEN IMRLSSLHKD RPVEPLDLAV FWVEFVMRHK GAPHLRPAAH 
       490        500        510        520        530    
DLTWYQYHSL DVIGFLLAVV LTVAFITFKC CAYGYRKCLG KKGRVKKAHK SKTH

Isoforms

- Isoform 2 of UDP-glucuronosyltransferase 1-4

Sequence View

        10         20         30         40         50         60 
MARGLQVPLP RLATGLLLLL SVQPWAESGK VLVVPTDGSP WLSMREALRE LHARGHQAVV 
        70         80         90        100        110        120 
LTPEVNMHIK EEKFFTLTAY AVPWTQKEFD RVTLGYTQGF FETEHLLKRY SRSMAIMNNV 
       130        140        150        160        170        180 
SLALHRCCVE LLHNEALIRH LNATSFDVVL TDPVNLCGAV LAKYLSIPAV FFWRYIPCDL 
       190        200        210        220        230        240 
DFKGTQCPNP SSYIPKLLTT NSDHMTFLQR VKNMLYPLAL SYICHTFSAP YASLASELFQ 
       250        260        270        280        290        300 
REVSVVDLVS YASVWLFRGD FVMDYPRPIM PNMVFIGGIN CANGKPLSQE FEAYINASGE 
       310        320        330        340        350        360 
HGIVVFSLGS MVSEIPEKKA MAIADALGKI PQTVLWRYTG TRPSNLANNT ILVKWLPQND 
       370        380        390        400        410        420 
LLGHPMTRAF ITHAGSHGVY ESICNGVPMV MMPLFGDQMD NAKRMETKGA GVTLNVLEMT 
       430        440        450        460        470        480 
SEDLENALKA VINDKSYKEN IMRLSSLHKD RPVEPLDLAV FWVEFVMRHK GAPHLRPAAH 
       490        500        510        520        530    
DLTWYQYHSL DVIGFLLAVV LTVAFITFKC CAYGYRKCLG KKGRVKKAHK SKTH



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P22310-1-unknown MARGLQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93810
    P22310-29-unknown GKVLVV... 29 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P22310-29-unknown GKVLVV... 29 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt114613

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KSKTH 534 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)