TopFIND 4.0

P22443: Aromatase

General Information

Protein names
- Aromatase
- 1.14.14.14 {ECO:0000250|UniProtKB:P11511}
- CYPXIX
- Cytochrome P-450AROM
- Cytochrome P450 19A1
- Estrogen synthase
Gene names Cyp19a1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P22443

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFLEMLNPMH YNVTIMVPET VPVSAMPLLL IMGLLLLIRN CESSSSIPGP GYCLGIGPLI 
        70         80         90        100        110        120 
SHGRFLWMGI GSACNYYNKM YGEFMRVWIS GEETLIISKS SSMVHVMKHS NYISRFGSKR 
       130        140        150        160        170        180 
GLQCIGMHEN GIIFNNNPSL WRTVRPFFMK ALTGPGLIRM VEVCVESIKQ HLDRLGDVTD 
       190        200        210        220        230        240 
NSGYVDVVTL MRHIMLDTSN TLFLGIPLDE SSIVKKIQGY FNAWQALLIK PNIFFKISWL 
       250        260        270        280        290        300 
YRKYERSVKD LKDEIEILVE KKRQKVSSAE KLEDCMDFAT DLIFAERRGD LTKENVNQCI 
       310        320        330        340        350        360 
LEMLIAAPDT MSVTLYVMLL LIAEYPEVET AILKEIHTVV GDRDIRIGDV QNLKVVENFI 
       370        380        390        400        410        420 
NESLRYQPVV DLVMRRALED DVIDGYPVKK GTNIILNIGR MHRLEYFPKP NEFTLENFEK 
       430        440        450        460        470        480 
NVPYRYFQPF GFGPRSCAGK YIAMVMMKVV LVTLLKRFHV KTLQKRCIEN MPKNNDLSLH 
       490        500    
LDEDSPIVEI IFRHIFNTPF LQCLYISL

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P22443-1-unknown MFLEML... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LYISL 508 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)