TopFIND 4.0

P22449: Hepatocyte nuclear factor 4-alpha

General Information

Protein names
- Hepatocyte nuclear factor 4-alpha
- HNF-4-alpha
- Nuclear receptor subfamily 2 group A member 1
- Transcription factor 14
- TCF-14
- Transcription factor HNF-4
Gene names Hnf4a
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P22449

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRLSKTLADM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGANLNS SNSLGVSALC 
        70         80         90        100        110        120 
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC 
       130        140        150        160        170        180 
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSQQITSPIS GINGDIRAKK 
       190        200        210        220        230        240 
IANITDVCES MKEQLLVLVE WAKYIPAFCE LLLDDQVALL RAHAGEHLLL GATKRSMVFK 
       250        260        270        280        290        300 
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYACLK AIIFFDPDAK 
       310        320        330        340        350        360 
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL 
       370        380        390        400        410        420 
FGMAKIDNLL QEMLLGGSAS DAPHAHHPLH PHLMQEHMGT NVIVANTMPS HLSNGQMCEW 
       430        440        450        460        470    
PRPRGQAATP ETPQPSPPSG SGSESYKLLP GAITTIVKPP SAIPQPTITK QEAI

Isoforms

- Isoform Short of Hepatocyte nuclear factor 4-alpha

Sequence View

        10         20         30         40         50         60 
MRLSKTLADM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGANLNS SNSLGVSALC 
        70         80         90        100        110        120 
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC 
       130        140        150        160        170        180 
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSQQITSPIS GINGDIRAKK 
       190        200        210        220        230        240 
IANITDVCES MKEQLLVLVE WAKYIPAFCE LLLDDQVALL RAHAGEHLLL GATKRSMVFK 
       250        260        270        280        290        300 
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYACLK AIIFFDPDAK 
       310        320        330        340        350        360 
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL 
       370        380        390        400        410        420 
FGMAKIDNLL QEMLLGGSAS DAPHAHHPLH PHLMQEHMGT NVIVANTMPS HLSNGQMCEW 
       430        440        450        460        470    
PRPRGQAATP ETPQPSPPSG SGSESYKLLP GAITTIVKPP SAIPQPTITK QEAI



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P22449-1-unknown MRLSKT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P22449-1-unknown MRLSKT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192757

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KQEAI 474 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KQEAI 474 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152703

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)