TopFIND 4.0

P22460: Potassium voltage-gated channel subfamily A member 5

General Information

Protein names
- Potassium voltage-gated channel subfamily A member 5
- HPCN1
- Voltage-gated potassium channel HK2
- Voltage-gated potassium channel subunit Kv1.5
Gene names KCNA5
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P22460

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEIALVPLEN GGAMTVRGGD EARAGCGQAT GGELQCPPTA GLSDGPKEPA PKGRGAQRDA 
        70         80         90        100        110        120 
DSGVRPLPPL PDPGVRPLPP LPEELPRPRR PPPEDEEEEG DPGLGTVEDQ ALGTASLHHQ 
       130        140        150        160        170        180 
RVHINISGLR FETQLGTLAQ FPNTLLGDPA KRLRYFDPLR NEYFFDRNRP SFDGILYYYQ 
       190        200        210        220        230        240 
SGGRLRRPVN VSLDVFADEI RFYQLGDEAM ERFREDEGFI KEEEKPLPRN EFQRQVWLIF 
       250        260        270        280        290        300 
EYPESSGSAR AIAIVSVLVI LISIITFCLE TLPEFRDERE LLRHPPAPHQ PPAPAPGANG 
       310        320        330        340        350        360 
SGVMAPPSGP TVAPLLPRTL ADPFFIVETT CVIWFTFELL VRFFACPSKA GFSRNIMNII 
       370        380        390        400        410        420 
DVVAIFPYFI TLGTELAEQQ PGGGGGGQNG QQAMSLAILR VIRLVRVFRI FKLSRHSKGL 
       430        440        450        460        470        480 
QILGKTLQAS MRELGLLIFF LFIGVILFSS AVYFAEADNQ GTHFSSIPDA FWWAVVTMTT 
       490        500        510        520        530        540 
VGYGDMRPIT VGGKIVGSLC AIAGVLTIAL PVPVIVSNFN YFYHRETDHE EPAVLKEEQG 
       550        560        570        580        590        600 
TQSQGPGLDR GVQRKVSGSR GSFCKAGGTL ENADSARRGS CPLEKCNVKA KSNVDLRRSL 
       610    
YALCLDTSRE TDL

Isoforms

- Isoform 2 of Potassium voltage-gated channel subfamily A member 5

Sequence View

        10         20         30         40         50         60 
MEIALVPLEN GGAMTVRGGD EARAGCGQAT GGELQCPPTA GLSDGPKEPA PKGRGAQRDA 
        70         80         90        100        110        120 
DSGVRPLPPL PDPGVRPLPP LPEELPRPRR PPPEDEEEEG DPGLGTVEDQ ALGTASLHHQ 
       130        140        150        160        170        180 
RVHINISGLR FETQLGTLAQ FPNTLLGDPA KRLRYFDPLR NEYFFDRNRP SFDGILYYYQ 
       190        200        210        220        230        240 
SGGRLRRPVN VSLDVFADEI RFYQLGDEAM ERFREDEGFI KEEEKPLPRN EFQRQVWLIF 
       250        260        270        280        290        300 
EYPESSGSAR AIAIVSVLVI LISIITFCLE TLPEFRDERE LLRHPPAPHQ PPAPAPGANG 
       310        320        330        340        350        360 
SGVMAPPSGP TVAPLLPRTL ADPFFIVETT CVIWFTFELL VRFFACPSKA GFSRNIMNII 
       370        380        390        400        410        420 
DVVAIFPYFI TLGTELAEQQ PGGGGGGQNG QQAMSLAILR VIRLVRVFRI FKLSRHSKGL 
       430        440        450        460        470        480 
QILGKTLQAS MRELGLLIFF LFIGVILFSS AVYFAEADNQ GTHFSSIPDA FWWAVVTMTT 
       490        500        510        520        530        540 
VGYGDMRPIT VGGKIVGSLC AIAGVLTIAL PVPVIVSNFN YFYHRETDHE EPAVLKEEQG 
       550        560        570        580        590        600 
TQSQGPGLDR GVQRKVSGSR GSFCKAGGTL ENADSARRGS CPLEKCNVKA KSNVDLRRSL 
       610    
YALCLDTSRE TDL



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P22460-1-unknown MEIALV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P22460-210-unknown MERFRE... 210 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78732

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RETDL 613 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RETDL 613 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74350

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)