TopFIND 4.0

P22518: Dual specificity protein kinase CLK1

General Information

Protein names
- Dual specificity protein kinase CLK1
- 2.7.12.1
- CDC-like kinase 1
- Protein kinase STY
Gene names Clk1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P22518

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRHSKRTYCP DWDERDWDYG TWRSSSSHKR KKRSHSSARE QKRCRYDHSK TTDSYYLESR 
        70         80         90        100        110        120 
SINEKAYHSR RYVDEYRNDY MGYEPGHPYG EPGSRYQMHS SKSSGRSGRS SYKSKHRSRH 
       130        140        150        160        170        180 
HTSQHHSHGK SHRRKRSRSV EDDEEGHLIC QSGDVLSARY EIVDTLGEGA FGKVVECIDH 
       190        200        210        220        230        240 
KVGGRRVAVK IVKNVDRYCE AAQSEIQVLE HLNTTDPHST FRCVQMLEWF EHRGHICIVF 
       250        260        270        280        290        300 
ELLGLSTYDF IKENSFLPFR MDHIRKMAYQ ICKSVNFLHS NKLTHTDLKP ENILFVKSDY 
       310        320        330        340        350        360 
TEAYNPKMKR DERTIVNPDI KVVDFGSATY DDEHHSTLVS TRHYRAPEVI LALGWSQPCD 
       370        380        390        400        410        420 
VWSIGCILIE YYLGFTVFPT HDSREHLAMM ERILGPLPKH MIQKTRKRRY FHHDRLDWDE 
       430        440        450        460        470        480 
HSSAGRYVSR RCKPLKEFML SQDAEHELLF DLIGKMLEYD PAKRITLKEA LKHPFFYPLK 
   
KHT

Isoforms

- Isoform Short of Dual specificity protein kinase CLK1

Sequence View

        10         20         30         40         50         60 
MRHSKRTYCP DWDERDWDYG TWRSSSSHKR KKRSHSSARE QKRCRYDHSK TTDSYYLESR 
        70         80         90        100        110        120 
SINEKAYHSR RYVDEYRNDY MGYEPGHPYG EPGSRYQMHS SKSSGRSGRS SYKSKHRSRH 
       130        140        150        160        170        180 
HTSQHHSHGK SHRRKRSRSV EDDEEGHLIC QSGDVLSARY EIVDTLGEGA FGKVVECIDH 
       190        200        210        220        230        240 
KVGGRRVAVK IVKNVDRYCE AAQSEIQVLE HLNTTDPHST FRCVQMLEWF EHRGHICIVF 
       250        260        270        280        290        300 
ELLGLSTYDF IKENSFLPFR MDHIRKMAYQ ICKSVNFLHS NKLTHTDLKP ENILFVKSDY 
       310        320        330        340        350        360 
TEAYNPKMKR DERTIVNPDI KVVDFGSATY DDEHHSTLVS TRHYRAPEVI LALGWSQPCD 
       370        380        390        400        410        420 
VWSIGCILIE YYLGFTVFPT HDSREHLAMM ERILGPLPKH MIQKTRKRRY FHHDRLDWDE 
       430        440        450        460        470        480 
HSSAGRYVSR RCKPLKEFML SQDAEHELLF DLIGKMLEYD PAKRITLKEA LKHPFFYPLK 
   
KHT



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P22518-1-unknown MRHSKR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P22518-1-unknown MRHSKR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70975

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LKKHT 483 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)