TopFIND 4.0

P22736: Nuclear receptor subfamily 4 group A member 1

General Information

Protein names
- Nuclear receptor subfamily 4 group A member 1
- Early response protein NAK1
- Nuclear hormone receptor NUR/77
- Nur77
- Orphan nuclear receptor HMR
- Orphan nuclear receptor TR3
- ST-59
- Testicular receptor 3
Gene names NR4A1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P22736

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPCIQAQYGT PAPSPGPRDH LASDPLTPEF IKPTMDLASP EAAPAAPTAL PSFSTFMDGY 
        70         80         90        100        110        120 
TGEFDTFLYQ LPGTVQPCSS ASSSASSTSS SSATSPASAS FKFEDFQVYG CYPGPLSGPV 
       130        140        150        160        170        180 
DEALSSSGSD YYGSPCSAPS PSTPSFQPPQ LSPWDGSFGH FSPSQTYEGL RAWTEQLPKA 
       190        200        210        220        230        240 
SGPPQPPAFF SFSPPTGPSP SLAQSPLKLF PSQATHQLGE GESYSMPTAF PGLAPTSPHL 
       250        260        270        280        290        300 
EGSGILDTPV TSTKARSGAP GGSEGRCAVC GDNASCQHYG VRTCEGCKGF FKRTVQKNAK 
       310        320        330        340        350        360 
YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP SKPKQPPDAS 
       370        380        390        400        410        420 
PANLLTSLVR AHLDSGPSTA KLDYSKFQEL VLPHFGKEDA GDVQQFYDLL SGSLEVIRKW 
       430        440        450        460        470        480 
AEKIPGFAEL SPADQDLLLE SAFLELFILR LAYRSKPGEG KLIFCSGLVL HRLQCARGFG 
       490        500        510        520        530        540 
DWIDSILAFS RSLHSLLVDV PAFACLSALV LITDRHGLQE PRRVEELQNR IASCLKEHVA 
       550        560        570        580        590    
AVAGEPQPAS CLSRLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPPIIDK IFMDTLPF

Isoforms

- Isoform 2 of Nuclear receptor subfamily 4 group A member 1 - Isoform 3 of Nuclear receptor subfamily 4 group A member 1

Sequence View

        10         20         30         40         50         60 
MPCIQAQYGT PAPSPGPRDH LASDPLTPEF IKPTMDLASP EAAPAAPTAL PSFSTFMDGY 
        70         80         90        100        110        120 
TGEFDTFLYQ LPGTVQPCSS ASSSASSTSS SSATSPASAS FKFEDFQVYG CYPGPLSGPV 
       130        140        150        160        170        180 
DEALSSSGSD YYGSPCSAPS PSTPSFQPPQ LSPWDGSFGH FSPSQTYEGL RAWTEQLPKA 
       190        200        210        220        230        240 
SGPPQPPAFF SFSPPTGPSP SLAQSPLKLF PSQATHQLGE GESYSMPTAF PGLAPTSPHL 
       250        260        270        280        290        300 
EGSGILDTPV TSTKARSGAP GGSEGRCAVC GDNASCQHYG VRTCEGCKGF FKRTVQKNAK 
       310        320        330        340        350        360 
YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP SKPKQPPDAS 
       370        380        390        400        410        420 
PANLLTSLVR AHLDSGPSTA KLDYSKFQEL VLPHFGKEDA GDVQQFYDLL SGSLEVIRKW 
       430        440        450        460        470        480 
AEKIPGFAEL SPADQDLLLE SAFLELFILR LAYRSKPGEG KLIFCSGLVL HRLQCARGFG 
       490        500        510        520        530        540 
DWIDSILAFS RSLHSLLVDV PAFACLSALV LITDRHGLQE PRRVEELQNR IASCLKEHVA 
       550        560        570        580        590    
AVAGEPQPAS CLSRLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPPIIDK IFMDTLPF         10         20         30         40         50         60 
MPCIQAQYGT PAPSPGPRDH LASDPLTPEF IKPTMDLASP EAAPAAPTAL PSFSTFMDGY 
        70         80         90        100        110        120 
TGEFDTFLYQ LPGTVQPCSS ASSSASSTSS SSATSPASAS FKFEDFQVYG CYPGPLSGPV 
       130        140        150        160        170        180 
DEALSSSGSD YYGSPCSAPS PSTPSFQPPQ LSPWDGSFGH FSPSQTYEGL RAWTEQLPKA 
       190        200        210        220        230        240 
SGPPQPPAFF SFSPPTGPSP SLAQSPLKLF PSQATHQLGE GESYSMPTAF PGLAPTSPHL 
       250        260        270        280        290        300 
EGSGILDTPV TSTKARSGAP GGSEGRCAVC GDNASCQHYG VRTCEGCKGF FKRTVQKNAK 
       310        320        330        340        350        360 
YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP SKPKQPPDAS 
       370        380        390        400        410        420 
PANLLTSLVR AHLDSGPSTA KLDYSKFQEL VLPHFGKEDA GDVQQFYDLL SGSLEVIRKW 
       430        440        450        460        470        480 
AEKIPGFAEL SPADQDLLLE SAFLELFILR LAYRSKPGEG KLIFCSGLVL HRLQCARGFG 
       490        500        510        520        530        540 
DWIDSILAFS RSLHSLLVDV PAFACLSALV LITDRHGLQE PRRVEELQNR IASCLKEHVA 
       550        560        570        580        590    
AVAGEPQPAS CLSRLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPPIIDK IFMDTLPF



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P22736-1-unknown MPCIQA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P22736-1-unknown MPCIQA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt83212
    P22736-1-unknown MPCIQA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt96500

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DTLPF 598 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...DTLPF 598 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78829

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)