P22748: Carbonic anhydrase 4

General Information

Protein names	- Carbonic anhydrase 4 - 4.2.1.1 - Carbonate dehydratase IV - Carbonic anhydrase IV - CA-IV
Gene names	CA4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P22748

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRMLLALLAL SAARPSASAE SHWCYEVQAE SSNYPCLVPV KWGGNCQKDR QSPINIVTTK
        70         80         90        100        110        120
AKVDKKLGRF FFSGYDKKQT WTVQNNGHSV MMLLENKASI SGGGLPAPYQ AKQLHLHWSD
       130        140        150        160        170        180
LPYKGSEHSL DGEHFAMEMH IVHEKEKGTS RNVKEAQDPE DEIAVLAFLV EAGTQVNEGF
       190        200        210        220        230        240
QPLVEALSNI PKPEMSTTMA ESSLLDLLPK EEKLRHYFRY LGSLTTPTCD EKVVWTVFRE
       250        260        270        280        290        300
PIQLHREQIL AFSQKLYYDK EQTVSMKDNV RPLQQLGQRT VIKSGAPGRP LPWALPALLG
       310
PMLACLLAGF LR

Isoforms

- Isoform 2 of Carbonic anhydrase 4

Sequence View

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P22748-19-unknown	AESHWC...	19	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P22748-91-unknown	MMLLEN...	91	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466964
P22748-285-unknown	GAPGRP...	285	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9871

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KGSEHS	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466964
...TVIKSG	284	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TVIKSG	284	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9871

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GPI8_HUMAN	284	IKSG.\|.GAPG	inferred from experiment	unknown	MEROPS	Sly WS	Okuyama T et al.:Carbonic anhydrase IV: role of ... (C13.005)	7625839,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

P22748: Carbonic anhydrase 4

General Information

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates