TopFIND 4.0

P22907: Porphobilinogen deaminase

General Information

Protein names
- Porphobilinogen deaminase
- PBG-D
- 2.5.1.61
- Hydroxymethylbilane synthase
- HMBS
- Pre-uroporphyrinogen synthase
Gene names Hmbs
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P22907

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGNGGAATT AEENGSKMRV IRVGTRKSQL ARIQTDTVVA MLKALYPGIQ FEIIAMSTTG 
        70         80         90        100        110        120 
DKILDTALSK IGEKSLFTKE LENALEKNEV DLVVHSLKDV PTILPPGFTI GAICKRENPC 
       130        140        150        160        170        180 
DAVVFHPKFI GKTLETLPEK SAVGTSSLRR VAQLQRKFPH LEFKSIRGNL NTRLRKLDEL 
       190        200        210        220        230        240 
QEFSAIVLAV AGLQRMGWQN RVGQILHPEE CMYAVGQGAL AVEVRAKDQD ILDLVSVLHD 
       250        260        270        280        290        300 
PETLLRCIAE RAFLRHLEGG CSVPVAVHTV MKDGQLYLTG GVWSLDGSDS MQETMQATIQ 
       310        320        330        340        350        360 
VPVQQEDGPE DDPQLVGITA RNIPRGAQLA AENLGISLAS LLLNKGAKNI LDVARQLNDV 
   
R

Isoforms

- Isoform 2 of Porphobilinogen deaminase - Isoform 2 of Porphobilinogen deaminase

Sequence View

        10         20         30         40         50         60 
MSGNGGAATT AEENGSKMRV IRVGTRKSQL ARIQTDTVVA MLKALYPGIQ FEIIAMSTTG 
        70         80         90        100        110        120 
DKILDTALSK IGEKSLFTKE LENALEKNEV DLVVHSLKDV PTILPPGFTI GAICKRENPC 
       130        140        150        160        170        180 
DAVVFHPKFI GKTLETLPEK SAVGTSSLRR VAQLQRKFPH LEFKSIRGNL NTRLRKLDEL 
       190        200        210        220        230        240 
QEFSAIVLAV AGLQRMGWQN RVGQILHPEE CMYAVGQGAL AVEVRAKDQD ILDLVSVLHD 
       250        260        270        280        290        300 
PETLLRCIAE RAFLRHLEGG CSVPVAVHTV MKDGQLYLTG GVWSLDGSDS MQETMQATIQ 
       310        320        330        340        350        360 
VPVQQEDGPE DDPQLVGITA RNIPRGAQLA AENLGISLAS LLLNKGAKNI LDVARQLNDV 
   
R         10         20         30         40         50         60 
MSGNGGAATT AEENGSKMRV IRVGTRKSQL ARIQTDTVVA MLKALYPGIQ FEIIAMSTTG 
        70         80         90        100        110        120 
DKILDTALSK IGEKSLFTKE LENALEKNEV DLVVHSLKDV PTILPPGFTI GAICKRENPC 
       130        140        150        160        170        180 
DAVVFHPKFI GKTLETLPEK SAVGTSSLRR VAQLQRKFPH LEFKSIRGNL NTRLRKLDEL 
       190        200        210        220        230        240 
QEFSAIVLAV AGLQRMGWQN RVGQILHPEE CMYAVGQGAL AVEVRAKDQD ILDLVSVLHD 
       250        260        270        280        290        300 
PETLLRCIAE RAFLRHLEGG CSVPVAVHTV MKDGQLYLTG GVWSLDGSDS MQETMQATIQ 
       310        320        330        340        350        360 
VPVQQEDGPE DDPQLVGITA RNIPRGAQLA AENLGISLAS LLLNKGAKNI LDVARQLNDV 
   
R



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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)