TopFIND 4.0

P23785: Progranulin {ECO:0000250|UniProtKB:P28799}

General Information

Protein names
- Progranulin {ECO:0000250|UniProtKB:P28799}
- PGRN {ECO:0000250|UniProtKB:P28799}
- Acrogranin {ECO:0000250|UniProtKB:P28798}
- Epithelin precursor {ECO:0000303|PubMed:1618805}
- Granulin precursor {ECO:0000303|PubMed:8243292}
- Proepithelin
- PEPI {ECO:0000250|UniProtKB:P28799}
- Paragranulin
- Granulin-1
- Granulin G
- Granulin-2
- Granulin F
- Granulin-3
- Epithelin-2 {ECO:0000303|PubMed:2236009}
- Granulin B
- Granulin-4
- Epithelin-1 {ECO:0000303|PubMed:2236009}
- Granulin A
- Granulin-5
- Granulin C
- Granulin-6
- Granulin D
- Granulin-7
- Granulin E
Gene names Grn
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P23785

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MWILVSWLAL VARLVAGTQC PDGQFCPVAC CLDQGGANYS CCNPLLDTWP IITSRRLDGS 
        70         80         90        100        110        120 
CQIRDHCPDG YSCLLTVSGT SSCCPFSEGV SCDDGQHCCP RGFHCSADGK SCSQISDSLL 
       130        140        150        160        170        180 
GAVQCPGSQF ECPDSATCCI MIDGSWGCCP MPQASCCEDR VHCCPHGASC DLVHTRCISP 
       190        200        210        220        230        240 
TGTHPLLKKF PAQRTNRAVA SFSVVCPDAK TQCPDDSTCC ELPTGKYGCC PMPNAICCSD 
       250        260        270        280        290        300 
HLHCCPQDTV CDLIQSKCIS KDYTTDLMTK LPGYPVNEVK CDLEVSCPDG YTCCRLNTGA 
       310        320        330        340        350        360 
WGCCPFTKAV CCEDHIHCCP AGFQCHTETG TCELGVLQVP WMKKVTASLS LPDPQILKND 
       370        380        390        400        410        420 
VPCDDFSSCP SNNTCCRLSS GDWGCCPMPE AVCCLDHQHC CPQGFKCMDE GYCQKGDRMV 
       430        440        450        460        470        480 
AGLEKMPVRQ TTLLQHGDIG CDQHTSCPVG QTCCPSLKGS WACCQLPHAV CCEDRQHCCP 
       490        500        510        520        530        540 
AGYTCNVKAR TCEKDAGSVQ PSMDLTFGSK VGNVECGAGH FCHDNQSCCK DSQGGWACCP 
       550        560        570        580    
YVKGVCCRDG RHCCPIGFHC SAKGTKCLRK KTPRWDILLR DPAPRPLL

Isoforms



Sequence View



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P23785-18-unknown TQCPDG... 18 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PRPLL 588 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)