TopFIND 4.0

P24008: 3-oxo-5-alpha-steroid 4-dehydrogenase 1

General Information

Protein names
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1
- 1.3.1.22
- SR type 1
- Steroid 5-alpha-reductase 1
- S5AR 1
Gene names Srd5a1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P24008

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVPLMELDEL CLLDMLVYLE GFMAFVSIVG LRSVGSPYGR YSPQWPGIRV PARPAWFIQE 
        70         80         90        100        110        120 
LPSMAWPLYE YIRPAAARLG NLPNRVLLAM FLIHYVQRTL VFPVLIRGGK PTLLVTFVLA 
       130        140        150        160        170        180 
FLFCTFNGYV QSRYLSQFAV YAEDWVTHPC FLTGFALWLV GMVINIHSDH ILRNLRKPGE 
       190        200        210        220        230        240 
TGYKIPRGGL FEYVSAANYF GELVEWCGFA LASWSLQGVV FALFTLSTLL TRAKQHHQWY 
       250    
HEKFEDYPKS RKILIPFVL

Isoforms

- Isoform Short of 3-oxo-5-alpha-steroid 4-dehydrogenase 1

Sequence View

        10         20         30         40         50         60 
MVPLMELDEL CLLDMLVYLE GFMAFVSIVG LRSVGSPYGR YSPQWPGIRV PARPAWFIQE 
        70         80         90        100        110        120 
LPSMAWPLYE YIRPAAARLG NLPNRVLLAM FLIHYVQRTL VFPVLIRGGK PTLLVTFVLA 
       130        140        150        160        170        180 
FLFCTFNGYV QSRYLSQFAV YAEDWVTHPC FLTGFALWLV GMVINIHSDH ILRNLRKPGE 
       190        200        210        220        230        240 
TGYKIPRGGL FEYVSAANYF GELVEWCGFA LASWSLQGVV FALFTLSTLL TRAKQHHQWY 
       250    
HEKFEDYPKS RKILIPFVL



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Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P24008-1-unknown MVPLME... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P24008-5-unknown MELDEL... 5 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193449

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IPFVL 259 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...IPFVL 259 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt153395

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)