TopFIND 4.0

P24462: Cytochrome P450 3A7 {ECO:0000303|PubMed:17178770}

General Information

Protein names
- Cytochrome P450 3A7 {ECO:0000303|PubMed:17178770}
- 1.14.14.- {ECO:0000269|PubMed:12865317, ECO:0000269|PubMed:14559847}
- CYPIIIA7
- Cytochrome P450-HFLA {ECO:0000303|PubMed:2492179}
- P450HLp2 {ECO:0000303|PubMed:2492179}
Gene names CYP3A7
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P24462

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLIPNLAVE TWLLLAVSLI LLYLYGTRTH GLFKKLGIPG PTPLPFLGNA LSFRKGYWTF 
        70         80         90        100        110        120 
DMECYKKYRK VWGIYDCQQP MLAITDPDMI KTVLVKECYS VFTNRRPFGP VGFMKNAISI 
       130        140        150        160        170        180 
AEDEEWKRIR SLLSPTFTSG KLKEMVPIIA QYGDVLVRNL RREAETGKPV TLKHVFGAYS 
       190        200        210        220        230        240 
MDVITSTSFG VSIDSLNNPQ DPFVENTKKL LRFNPLDPFV LSIKVFPFLT PILEALNITV 
       250        260        270        280        290        300 
FPRKVISFLT KSVKQIKEGR LKETQKHRVD FLQLMIDSQN SKDSETHKAL SDLELMAQSI 
       310        320        330        340        350        360 
IFIFAGYETT SSVLSFIIYE LATHPDVQQK VQKEIDTVLP NKAPPTYDTV LQLEYLDMVV 
       370        380        390        400        410        420 
NETLRLFPVA MRLERVCKKD VEINGMFIPK GVVVMIPSYV LHHDPKYWTE PEKFLPERFS 
       430        440        450        460        470        480 
KKNKDNIDPY IYTPFGSGPR NCIGMRFALV NMKLALVRVL QNFSFKPCKE TQIPLKLRFG 
       490        500    
GLLLTEKPIV LKAESRDETV SGA

Isoforms

- Isoform 2 of Cytochrome P450 3A7

Sequence View

        10         20         30         40         50         60 
MDLIPNLAVE TWLLLAVSLI LLYLYGTRTH GLFKKLGIPG PTPLPFLGNA LSFRKGYWTF 
        70         80         90        100        110        120 
DMECYKKYRK VWGIYDCQQP MLAITDPDMI KTVLVKECYS VFTNRRPFGP VGFMKNAISI 
       130        140        150        160        170        180 
AEDEEWKRIR SLLSPTFTSG KLKEMVPIIA QYGDVLVRNL RREAETGKPV TLKHVFGAYS 
       190        200        210        220        230        240 
MDVITSTSFG VSIDSLNNPQ DPFVENTKKL LRFNPLDPFV LSIKVFPFLT PILEALNITV 
       250        260        270        280        290        300 
FPRKVISFLT KSVKQIKEGR LKETQKHRVD FLQLMIDSQN SKDSETHKAL SDLELMAQSI 
       310        320        330        340        350        360 
IFIFAGYETT SSVLSFIIYE LATHPDVQQK VQKEIDTVLP NKAPPTYDTV LQLEYLDMVV 
       370        380        390        400        410        420 
NETLRLFPVA MRLERVCKKD VEINGMFIPK GVVVMIPSYV LHHDPKYWTE PEKFLPERFS 
       430        440        450        460        470        480 
KKNKDNIDPY IYTPFGSGPR NCIGMRFALV NMKLALVRVL QNFSFKPCKE TQIPLKLRFG 
       490        500    
GLLLTEKPIV LKAESRDETV SGA



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P24462-1-unknown MDLIPN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TVSGA 503 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)