P24527: Leukotriene A-4 hydrolase
| Protein names | - Leukotriene A-4 hydrolase - LTA-4 hydrolase - 3.3.2.6 - Leukotriene A(4) hydrolase |
|---|---|
| Gene names | Lta4h |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | M01.004 |
| Chromosome location | |
| UniProt ID | P24527 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPEVADTCSL ASPASVCRTQ HLHLRCSVDF ARRTLTGTAA LTVQSQEENL RSLTLDTKDL
70 80 90 100 110 120
TIEKVVINGQ EVKYTLGESQ GYKGSPMEIS LPIALSKNQE IVIEISFETS PKSSALQWLT
130 140 150 160 170 180
PEQTSGKQHP YLFSQCQAIH CRAILPCQDT PSVKLTYTAE VSVPKELVAL MSAIRDGEAP
190 200 210 220 230 240
DPEDPSRKIY RFNQRVPIPC YLIALVVGAL ESRQIGPRTL VWSEKEQVEK SANEFSETES
250 260 270 280 290 300
MLKIAEDLGG PYVWGQYDLL VLPPSFPYGG MENPCLTFVT PTLLAGDKSL SNVIAHEISH
310 320 330 340 350 360
SWTGNLVTNK TWDHFWLNEG HTVYLERHIC GRLFGEKFRH FHALGGWGEL QNTIKTFGES
370 380 390 400 410 420
HPFTKLVVDL KDVDPDVAYS SIPYEKGFAL LFYLEQLLGG PEVFLGFLKA YVKKFSYQSV
430 440 450 460 470 480
TTDDWKSFLY SHFKDKVDLL NQVDWNTWLY APGLPPVKPN YDVTLTNACI ALSQRWVTAK
490 500 510 520 530 540
EEDLSSFSIA DLKDLSSHQL NEFLAQVLQK APLPLGHIKR MQEVYNFNAI NNSEIRFRWL
550 560 570 580 590 600
RLCIQSKWEE AIPLALKMAT EQGRMKFTRP LFKDLAAFDK SHDQAVHTYQ EHKASMHPVT
610
AMLVGRDLKV D
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P24527-2-unknown | PEVADT... | 2 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P24527-2-unknown | PEVADT... | 2 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
| P24527-41-unknown | LTVQSQ... | 41 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29861 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...TGTAAL | 40 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29861 | |||
| ...DLKVD | 611 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CATE_MOUSE | 40 | TAAL.|.LTVQ | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> LKHA4_MOUSE @40 |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|