TopFIND 4.0

P24942: Excitatory amino acid transporter 1

General Information

Protein names
- Excitatory amino acid transporter 1
- Glial glutamate transporter
- Sodium-dependent glutamate/aspartate transporter 1 {ECO:0000303|PubMed:11086157}
- GLAST {ECO:0000303|PubMed:1279699}
- GLAST-1 {ECO:0000303|PubMed:11086157}
- Solute carrier family 1 member 3
Gene names Slc1a3
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P24942

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTKSNGEEPR MGSRMERFQQ GVRKRTLLAK KKVQNITKED VKSYLFRNAF VLLTVSAVIV 
        70         80         90        100        110        120 
GTILGFALRP YKMSYREVKY FSFPGELLMR MLQMLVLPLI ISSLVTGMAA LDSKASGKMG 
       130        140        150        160        170        180 
MRAVVYYMTT TIIAVVIGII IVIIIHPGKG TKENMYREGK IVQVTAADAF LDLIRNMFPP 
       190        200        210        220        230        240 
NLVEACFKQF KTSYEKRSFK VPIQANETLL GAVINNVSEA METLTRIREE MVPVPGSVNG 
       250        260        270        280        290        300 
VNALGLVVFS MCFGFVIGNM KEQGQALREF FDSLNEAIMR LVAVIMWYAP LGILFLIAGK 
       310        320        330        340        350        360 
ILEMEDMGVI GGQLAMYTVT VIVGLLIHAV IVLPLLYFLV TRKNPWVFIG GLLQALITAL 
       370        380        390        400        410        420 
GTSSSSATLP ITFKCLEENN GVDKRITRFV LPVGATINMD GTALYEALAA IFIAQVNNFD 
       430        440        450        460        470        480 
LNFGQIITIS ITATAASIGA AGIPQAGLVT MVIVLTSVGL PTDDITLIIA VDWFLDRLRT 
       490        500        510        520        530        540 
TTNVLGDSLG AGIVEHLSRH ELKNRDVEMG NSVIEENEMK KPYQLIAQDN EPEKPVADSE 
   
TKM

Isoforms

- Isoform GLAST-1A of Excitatory amino acid transporter 1

Sequence View

        10         20         30         40         50         60 
MTKSNGEEPR MGSRMERFQQ GVRKRTLLAK KKVQNITKED VKSYLFRNAF VLLTVSAVIV 
        70         80         90        100        110        120 
GTILGFALRP YKMSYREVKY FSFPGELLMR MLQMLVLPLI ISSLVTGMAA LDSKASGKMG 
       130        140        150        160        170        180 
MRAVVYYMTT TIIAVVIGII IVIIIHPGKG TKENMYREGK IVQVTAADAF LDLIRNMFPP 
       190        200        210        220        230        240 
NLVEACFKQF KTSYEKRSFK VPIQANETLL GAVINNVSEA METLTRIREE MVPVPGSVNG 
       250        260        270        280        290        300 
VNALGLVVFS MCFGFVIGNM KEQGQALREF FDSLNEAIMR LVAVIMWYAP LGILFLIAGK 
       310        320        330        340        350        360 
ILEMEDMGVI GGQLAMYTVT VIVGLLIHAV IVLPLLYFLV TRKNPWVFIG GLLQALITAL 
       370        380        390        400        410        420 
GTSSSSATLP ITFKCLEENN GVDKRITRFV LPVGATINMD GTALYEALAA IFIAQVNNFD 
       430        440        450        460        470        480 
LNFGQIITIS ITATAASIGA AGIPQAGLVT MVIVLTSVGL PTDDITLIIA VDWFLDRLRT 
       490        500        510        520        530        540 
TTNVLGDSLG AGIVEHLSRH ELKNRDVEMG NSVIEENEMK KPYQLIAQDN EPEKPVADSE 
   
TKM



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P24942-1-unknown MTKSNG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P24942-1-unknown MTKSNG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192560

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SETKM 543 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SETKM 543 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152506

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)