TopFIND 4.0

P25189: Myelin protein P0

General Information

Protein names
- Myelin protein P0
- Myelin peripheral protein
- MPP
- Myelin protein zero
Gene names MPZ
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P25189

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAPGAPSSSP SPILAVLLFS SLVLSPAQAI VVYTDREVHG AVGSRVTLHC SFWSSEWVSD 
        70         80         90        100        110        120 
DISFTWRYQP EGGRDAISIF HYAKGQPYID EVGTFKERIQ WVGDPRWKDG SIVIHNLDYS 
       130        140        150        160        170        180 
DNGTFTCDVK NPPDIVGKTS QVTLYVFEKV PTRYGVVLGA VIGGVLGVVL LLLLLFYVVR 
       190        200        210        220        230        240 
YCWLRRQAAL QRRLSAMEKG KLHKPGKDAS KRGRQTPVLY AMLDHSRSTK AVSEKKAKGL 
   
GESRKDKK

Isoforms

- Isoform L-MPZ of Myelin protein P0

Sequence View

        10         20         30         40         50         60 
MAPGAPSSSP SPILAVLLFS SLVLSPAQAI VVYTDREVHG AVGSRVTLHC SFWSSEWVSD 
        70         80         90        100        110        120 
DISFTWRYQP EGGRDAISIF HYAKGQPYID EVGTFKERIQ WVGDPRWKDG SIVIHNLDYS 
       130        140        150        160        170        180 
DNGTFTCDVK NPPDIVGKTS QVTLYVFEKV PTRYGVVLGA VIGGVLGVVL LLLLLFYVVR 
       190        200        210        220        230        240 
YCWLRRQAAL QRRLSAMEKG KLHKPGKDAS KRGRQTPVLY AMLDHSRSTK AVSEKKAKGL 
   
GESRKDKK



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Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RKDKK 248 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RKDKK 248 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt92090

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)