TopFIND 4.0

P25445: Tumor necrosis factor receptor superfamily member 6

General Information

Protein names
- Tumor necrosis factor receptor superfamily member 6
- Apo-1 antigen
- Apoptosis-mediating surface antigen FAS
- FASLG receptor
- CD95
Gene names FAS
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P25445

4

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH 
        70         80         90        100        110        120 
KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT 
       130        140        150        160        170        180 
RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL 
       190        200        210        220        230        240 
LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM 
       250        260        270        280        290        300 
TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK 
       310        320        330    
ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV

Isoforms

- Isoform 2 of Tumor necrosis factor receptor superfamily member 6 - Isoform 3 of Tumor necrosis factor receptor superfamily member 6 - Isoform 4 of Tumor necrosis factor receptor superfamily member 6 - Isoform 5 of Tumor necrosis factor receptor superfamily member 6 - Isoform 6 of Tumor necrosis factor receptor superfamily member 6 - Isoform 7 of Tumor necrosis factor receptor superfamily member 6

Sequence View

        10         20         30         40         50         60 
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH 
        70         80         90        100        110        120 
KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT 
       130        140        150        160        170        180 
RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL 
       190        200        210        220        230        240 
LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM 
       250        260        270        280        290        300 
TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK 
       310        320        330    
ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV         10         20         30         40         50         60 
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH 
        70         80         90        100        110        120 
KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT 
       130        140        150        160        170        180 
RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL 
       190        200        210        220        230        240 
LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM 
       250        260        270        280        290        300 
TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK 
       310        320        330    
ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV         10         20         30         40         50         60 
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH 
        70         80         90        100        110        120 
KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT 
       130        140        150        160        170        180 
RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL 
       190        200        210        220        230        240 
LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM 
       250        260        270        280        290        300 
TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK 
       310        320        330    
ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV         10         20         30         40         50         60 
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH 
        70         80         90        100        110        120 
KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT 
       130        140        150        160        170        180 
RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL 
       190        200        210        220        230        240 
LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM 
       250        260        270        280        290        300 
TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK 
       310        320        330    
ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV         10         20         30         40         50         60 
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH 
        70         80         90        100        110        120 
KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT 
       130        140        150        160        170        180 
RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL 
       190        200        210        220        230        240 
LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM 
       250        260        270        280        290        300 
TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK 
       310        320        330    
ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV         10         20         30         40         50         60 
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH 
        70         80         90        100        110        120 
KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT 
       130        140        150        160        170        180 
RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL 
       190        200        210        220        230        240 
LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM 
       250        260        270        280        290        300 
TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK 
       310        320        330    
ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV



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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)