TopFIND 4.0

P26439: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

General Information

Protein names
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II
- 3-beta-HSD II
- 3-beta-HSD adrenal and gonadal type
- 3-beta-hydroxy-Delta(5)-steroid dehydrogenase
- 1.1.1.145
- 3-beta-hydroxy-5-ene steroid dehydrogenase
- Progesterone reductase
- Steroid Delta-isomerase
- 5.3.3.1
- Delta-5-3-ketosteroid isomerase
Gene names HSD3B2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P26439

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGWSCLVTGA GGLLGQRIVR LLVEEKELKE IRALDKAFRP ELREEFSKLQ NRTKLTVLEG 
        70         80         90        100        110        120 
DILDEPFLKR ACQDVSVVIH TACIIDVFGV THRESIMNVN VKGTQLLLEA CVQASVPVFI 
       130        140        150        160        170        180 
YTSSIEVAGP NSYKEIIQNG HEEEPLENTW PTPYPYSKKL AEKAVLAANG WNLKNGDTLY 
       190        200        210        220        230        240 
TCALRPTYIY GEGGPFLSAS INEALNNNGI LSSVGKFSTV NPVYVGNVAW AHILALRALR 
       250        260        270        280        290        300 
DPKKAPSVRG QFYYISDDTP HQSYDNLNYI LSKEFGLRLD SRWSLPLTLM YWIGFLLEVV 
       310        320        330        340        350        360 
SFLLSPIYSY QPPFNRHTVT LSNSVFTFSY KKAQRDLAYK PLYSWEEAKQ KTVEWVGSLV 
       370    
DRHKETLKSK TQ

Isoforms

- Isoform 2 of 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

Sequence View

        10         20         30         40         50         60 
MGWSCLVTGA GGLLGQRIVR LLVEEKELKE IRALDKAFRP ELREEFSKLQ NRTKLTVLEG 
        70         80         90        100        110        120 
DILDEPFLKR ACQDVSVVIH TACIIDVFGV THRESIMNVN VKGTQLLLEA CVQASVPVFI 
       130        140        150        160        170        180 
YTSSIEVAGP NSYKEIIQNG HEEEPLENTW PTPYPYSKKL AEKAVLAANG WNLKNGDTLY 
       190        200        210        220        230        240 
TCALRPTYIY GEGGPFLSAS INEALNNNGI LSSVGKFSTV NPVYVGNVAW AHILALRALR 
       250        260        270        280        290        300 
DPKKAPSVRG QFYYISDDTP HQSYDNLNYI LSKEFGLRLD SRWSLPLTLM YWIGFLLEVV 
       310        320        330        340        350        360 
SFLLSPIYSY QPPFNRHTVT LSNSVFTFSY KKAQRDLAYK PLYSWEEAKQ KTVEWVGSLV 
       370    
DRHKETLKSK TQ



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P26439-1-unknown MGWSCL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P26439-1-unknown MGWSCL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65761

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KSKTQ 372 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)