TopFIND 4.0

P26951: Interleukin-3 receptor subunit alpha

General Information

Protein names
- Interleukin-3 receptor subunit alpha
- IL-3 receptor subunit alpha
- IL-3R subunit alpha
- IL-3R-alpha
- IL-3RA
- CD123
Gene names IL3RA
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P26951

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVLLWLTLLL IALPCLLQTK EDPNPPITNL RMKAKAQQLT WDLNRNVTDI ECVKDADYSM 
        70         80         90        100        110        120 
PAVNNSYCQF GAISLCEVTN YTVRVANPPF STWILFPENS GKPWAGAENL TCWIHDVDFL 
       130        140        150        160        170        180 
SCSWAVGPGA PADVQYDLYL NVANRRQQYE CLHYKTDAQG TRIGCRFDDI SRLSSGSQSS 
       190        200        210        220        230        240 
HILVRGRSAA FGIPCTDKFV VFSQIEILTP PNMTAKCNKT HSFMHWKMRS HFNRKFRYEL 
       250        260        270        280        290        300 
QIQKRMQPVI TEQVRDRTSF QLLNPGTYTV QIRARERVYE FLSAWSTPQR FECDQEEGAN 
       310        320        330        340        350        360 
TRAWRTSLLI ALGTLLALVC VFVICRRYLV MQRLFPRIPH MKDPIGDSFQ NDKLVVWEAG 
       370    
KAGLEECLVT EVQVVQKT

Isoforms

- Isoform 2 of Interleukin-3 receptor subunit alpha - Isoform 2 of Interleukin-3 receptor subunit alpha

Sequence View

        10         20         30         40         50         60 
MVLLWLTLLL IALPCLLQTK EDPNPPITNL RMKAKAQQLT WDLNRNVTDI ECVKDADYSM 
        70         80         90        100        110        120 
PAVNNSYCQF GAISLCEVTN YTVRVANPPF STWILFPENS GKPWAGAENL TCWIHDVDFL 
       130        140        150        160        170        180 
SCSWAVGPGA PADVQYDLYL NVANRRQQYE CLHYKTDAQG TRIGCRFDDI SRLSSGSQSS 
       190        200        210        220        230        240 
HILVRGRSAA FGIPCTDKFV VFSQIEILTP PNMTAKCNKT HSFMHWKMRS HFNRKFRYEL 
       250        260        270        280        290        300 
QIQKRMQPVI TEQVRDRTSF QLLNPGTYTV QIRARERVYE FLSAWSTPQR FECDQEEGAN 
       310        320        330        340        350        360 
TRAWRTSLLI ALGTLLALVC VFVICRRYLV MQRLFPRIPH MKDPIGDSFQ NDKLVVWEAG 
       370    
KAGLEECLVT EVQVVQKT         10         20         30         40         50         60 
MVLLWLTLLL IALPCLLQTK EDPNPPITNL RMKAKAQQLT WDLNRNVTDI ECVKDADYSM 
        70         80         90        100        110        120 
PAVNNSYCQF GAISLCEVTN YTVRVANPPF STWILFPENS GKPWAGAENL TCWIHDVDFL 
       130        140        150        160        170        180 
SCSWAVGPGA PADVQYDLYL NVANRRQQYE CLHYKTDAQG TRIGCRFDDI SRLSSGSQSS 
       190        200        210        220        230        240 
HILVRGRSAA FGIPCTDKFV VFSQIEILTP PNMTAKCNKT HSFMHWKMRS HFNRKFRYEL 
       250        260        270        280        290        300 
QIQKRMQPVI TEQVRDRTSF QLLNPGTYTV QIRARERVYE FLSAWSTPQR FECDQEEGAN 
       310        320        330        340        350        360 
TRAWRTSLLI ALGTLLALVC VFVICRRYLV MQRLFPRIPH MKDPIGDSFQ NDKLVVWEAG 
       370    
KAGLEECLVT EVQVVQKT



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P26951-1-unknown MVLLWL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77787
    P26951-19-unknown TKEDPN... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)