TopFIND 4.0

P27889: Hepatocyte nuclear factor 1-beta

General Information

Protein names
- Hepatocyte nuclear factor 1-beta
- HNF-1-beta
- HNF-1B
- Homeoprotein LFB3
- Transcription factor 2
- TCF-2
Gene names Hnf1b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P27889

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVSKLTSLQQ ELLSALLSSG VTKEVLIQAL EELLPSPNFG VKLETLPLSP GSGADLDTKP 
        70         80         90        100        110        120 
VFHTLTNGHA KGRLSGDEGS EDGDDYDTPP ILKELQALNT EEAAEQRAEV DRMLSEDPWR 
       130        140        150        160        170        180 
AAKMIKGYMQ QHNIPQREVV DVTGLNQSHL SQHLNKGTPM KTQKRAALYT WYVRKQREIL 
       190        200        210        220        230        240 
RQFNQTVQSS GNMTDKSSQD QLLFLFPEFS QQNQGPGQSE DTCSEPTNKK MRRNRFKWGP 
       250        260        270        280        290        300 
ASQQILYQAY DRQKNPSKEE REALVEECNR AECLQRGVSP SKAHGLGSNL VTEVRVYNWF 
       310        320        330        340        350        360 
ANRRKEEAFR QKLAMDAYSS NQTHNLNPLL THGSPHHQPS SSPPNKMSGV RYNQPGNNEV 
       370        380        390        400        410        420 
TSSSTISHHG NSAMVTSQSV LQQVSPASLD PGHSLLSPDS KMQITVSGGG LPPVSTLTNI 
       430        440        450        460        470        480 
HSLSHHNPQQ SQNLIMTPLS GVMAIAQSLN TSQAQGVPVI NSVASSLAAL QPVQFSQQLH 
       490        500        510        520        530        540 
SPHQQPLMQQ SPGSHMAQQP FMAAVTQLQN SHMYAHKQEP PQYSHTSRFP SAMVVTDTSS 
       550    
INTLTSMSSS KQCPLQAW

Isoforms

- Isoform 2 of Hepatocyte nuclear factor 1-beta - Isoform 3 of Hepatocyte nuclear factor 1-beta - Isoform 4 of Hepatocyte nuclear factor 1-beta

Sequence View

        10         20         30         40         50         60 
MVSKLTSLQQ ELLSALLSSG VTKEVLIQAL EELLPSPNFG VKLETLPLSP GSGADLDTKP 
        70         80         90        100        110        120 
VFHTLTNGHA KGRLSGDEGS EDGDDYDTPP ILKELQALNT EEAAEQRAEV DRMLSEDPWR 
       130        140        150        160        170        180 
AAKMIKGYMQ QHNIPQREVV DVTGLNQSHL SQHLNKGTPM KTQKRAALYT WYVRKQREIL 
       190        200        210        220        230        240 
RQFNQTVQSS GNMTDKSSQD QLLFLFPEFS QQNQGPGQSE DTCSEPTNKK MRRNRFKWGP 
       250        260        270        280        290        300 
ASQQILYQAY DRQKNPSKEE REALVEECNR AECLQRGVSP SKAHGLGSNL VTEVRVYNWF 
       310        320        330        340        350        360 
ANRRKEEAFR QKLAMDAYSS NQTHNLNPLL THGSPHHQPS SSPPNKMSGV RYNQPGNNEV 
       370        380        390        400        410        420 
TSSSTISHHG NSAMVTSQSV LQQVSPASLD PGHSLLSPDS KMQITVSGGG LPPVSTLTNI 
       430        440        450        460        470        480 
HSLSHHNPQQ SQNLIMTPLS GVMAIAQSLN TSQAQGVPVI NSVASSLAAL QPVQFSQQLH 
       490        500        510        520        530        540 
SPHQQPLMQQ SPGSHMAQQP FMAAVTQLQN SHMYAHKQEP PQYSHTSRFP SAMVVTDTSS 
       550    
INTLTSMSSS KQCPLQAW         10         20         30         40         50         60 
MVSKLTSLQQ ELLSALLSSG VTKEVLIQAL EELLPSPNFG VKLETLPLSP GSGADLDTKP 
        70         80         90        100        110        120 
VFHTLTNGHA KGRLSGDEGS EDGDDYDTPP ILKELQALNT EEAAEQRAEV DRMLSEDPWR 
       130        140        150        160        170        180 
AAKMIKGYMQ QHNIPQREVV DVTGLNQSHL SQHLNKGTPM KTQKRAALYT WYVRKQREIL 
       190        200        210        220        230        240 
RQFNQTVQSS GNMTDKSSQD QLLFLFPEFS QQNQGPGQSE DTCSEPTNKK MRRNRFKWGP 
       250        260        270        280        290        300 
ASQQILYQAY DRQKNPSKEE REALVEECNR AECLQRGVSP SKAHGLGSNL VTEVRVYNWF 
       310        320        330        340        350        360 
ANRRKEEAFR QKLAMDAYSS NQTHNLNPLL THGSPHHQPS SSPPNKMSGV RYNQPGNNEV 
       370        380        390        400        410        420 
TSSSTISHHG NSAMVTSQSV LQQVSPASLD PGHSLLSPDS KMQITVSGGG LPPVSTLTNI 
       430        440        450        460        470        480 
HSLSHHNPQQ SQNLIMTPLS GVMAIAQSLN TSQAQGVPVI NSVASSLAAL QPVQFSQQLH 
       490        500        510        520        530        540 
SPHQQPLMQQ SPGSHMAQQP FMAAVTQLQN SHMYAHKQEP PQYSHTSRFP SAMVVTDTSS 
       550    
INTLTSMSSS KQCPLQAW         10         20         30         40         50         60 
MVSKLTSLQQ ELLSALLSSG VTKEVLIQAL EELLPSPNFG VKLETLPLSP GSGADLDTKP 
        70         80         90        100        110        120 
VFHTLTNGHA KGRLSGDEGS EDGDDYDTPP ILKELQALNT EEAAEQRAEV DRMLSEDPWR 
       130        140        150        160        170        180 
AAKMIKGYMQ QHNIPQREVV DVTGLNQSHL SQHLNKGTPM KTQKRAALYT WYVRKQREIL 
       190        200        210        220        230        240 
RQFNQTVQSS GNMTDKSSQD QLLFLFPEFS QQNQGPGQSE DTCSEPTNKK MRRNRFKWGP 
       250        260        270        280        290        300 
ASQQILYQAY DRQKNPSKEE REALVEECNR AECLQRGVSP SKAHGLGSNL VTEVRVYNWF 
       310        320        330        340        350        360 
ANRRKEEAFR QKLAMDAYSS NQTHNLNPLL THGSPHHQPS SSPPNKMSGV RYNQPGNNEV 
       370        380        390        400        410        420 
TSSSTISHHG NSAMVTSQSV LQQVSPASLD PGHSLLSPDS KMQITVSGGG LPPVSTLTNI 
       430        440        450        460        470        480 
HSLSHHNPQQ SQNLIMTPLS GVMAIAQSLN TSQAQGVPVI NSVASSLAAL QPVQFSQQLH 
       490        500        510        520        530        540 
SPHQQPLMQQ SPGSHMAQQP FMAAVTQLQN SHMYAHKQEP PQYSHTSRFP SAMVVTDTSS 
       550    
INTLTSMSSS KQCPLQAW



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)