P27918: Properdin

General Information

Protein names	- Properdin - Complement factor P
Gene names	CFP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P27918

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MITEGAQAPR LLLPPLLLLL TLPATGSDPV LCFTQYEESS GKCKGLLGGG VSVEDCCLNT
        70         80         90        100        110        120
AFAYQKRSGG LCQPCRSPRW SLWSTWAPCS VTCSEGSQLR YRRCVGWNGQ CSGKVAPGTL
       130        140        150        160        170        180
EWQLQACEDQ QCCPEMGGWS GWGPWEPCSV TCSKGTRTRR RACNHPAPKC GGHCPGQAQE
       190        200        210        220        230        240
SEACDTQQVC PTHGAWATWG PWTPCSASCH GGPHEPKETR SRKCSAPEPS QKPPGKPCPG
       250        260        270        280        290        300
LAYEQRRCTG LPPCPVAGGW GPWGPVSPCP VTCGLGQTME QRTCNHPVPQ HGGPFCAGDA
       310        320        330        340        350        360
TRTHICNTAV PCPVDGEWDS WGEWSPCIRR NMKSISCQEI PGQQSRGRTC RGRKFDGHRC
       370        380        390        400        410        420
AGQQQDIRHC YSIQHCPLKG SWSEWSTWGL CMPPCGPNPT RARQRLCTPL LPKYPPTVSM
       430        440        450        460
VEGQGEKNVT FWGRPLPRCE ELQGQKLVVE EKRPCLHVPA CKDPEEEEL

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
P27918-28-unknown	DPVLCF...	28	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P27918-136-unknown	MGGWSG...	136	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418258
P27918-334-unknown	SISCQE...	334		unknown		Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P27918-360-unknown	CAGQQQ...	360		unknown		Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GDATRT	302	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418258
...LPKYPP	415	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000366204
...EEEEL	469	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)