TopFIND 4.0

P27930: Interleukin-1 receptor type 2

General Information

Protein names
- Interleukin-1 receptor type 2
- IL-1R-2
- IL-1RT-2
- IL-1RT2
- CD121 antigen-like family member B
- CDw121b
- IL-1 type II receptor
- Interleukin-1 receptor beta
- IL-1R-beta
- Interleukin-1 receptor type II
- CD121b
- Interleukin-1 receptor type 2, membrane form
- mIL-1R2
- mIL-1RII
- Interleukin-1 receptor type 2, soluble form
- sIL-1R2
- sIL-1RII
Gene names IL1R2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P27930

2

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLRLYVLVMG VSAFTLQPAA HTGAARSCRF RGRHYKREFR LEGEPVALRC PQVPYWLWAS 
        70         80         90        100        110        120 
VSPRINLTWH KNDSARTVPG EEETRMWAQD GALWLLPALQ EDSGTYVCTT RNASYCDKMS 
       130        140        150        160        170        180 
IELRVFENTD AFLPFISYPQ ILTLSTSGVL VCPDLSEFTR DKTDVKIQWY KDSLLLDKDN 
       190        200        210        220        230        240 
EKFLSVRGTT HLLVHDVALE DAGYYRCVLT FAHEGQQYNI TRSIELRIKK KKEETIPVII 
       250        260        270        280        290        300 
SPLKTISASL GSRLTIPCKV FLGTGTPLTT MLWWTANDTH IESAYPGGRV TEGPRQEYSE 
       310        320        330        340        350        360 
NNENYIEVPL IFDPVTREDL HMDFKCVVHN TLSFQTLRTT VKEASSTFSW GIVLAPLSLA 
       370        380        390    
FLVLGGIWMH RRCKHRTGKA DGLTVLWPHH QDFQSYPK

Isoforms

- Isoform Short of Interleukin-1 receptor type 2

Sequence View

        10         20         30         40         50         60 
MLRLYVLVMG VSAFTLQPAA HTGAARSCRF RGRHYKREFR LEGEPVALRC PQVPYWLWAS 
        70         80         90        100        110        120 
VSPRINLTWH KNDSARTVPG EEETRMWAQD GALWLLPALQ EDSGTYVCTT RNASYCDKMS 
       130        140        150        160        170        180 
IELRVFENTD AFLPFISYPQ ILTLSTSGVL VCPDLSEFTR DKTDVKIQWY KDSLLLDKDN 
       190        200        210        220        230        240 
EKFLSVRGTT HLLVHDVALE DAGYYRCVLT FAHEGQQYNI TRSIELRIKK KKEETIPVII 
       250        260        270        280        290        300 
SPLKTISASL GSRLTIPCKV FLGTGTPLTT MLWWTANDTH IESAYPGGRV TEGPRQEYSE 
       310        320        330        340        350        360 
NNENYIEVPL IFDPVTREDL HMDFKCVVHN TLSFQTLRTT VKEASSTFSW GIVLAPLSLA 
       370        380        390    
FLVLGGIWMH RRCKHRTGKA DGLTVLWPHH QDFQSYPK



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P27930-1-unknown MLRLYV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77736
    P27930-14-unknown FTLQPA... 14 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P27930-14-unknown FTLQPA... 14 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111767

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)