TopFIND 4.0

P28069: Pituitary-specific positive transcription factor 1

General Information

Protein names
- Pituitary-specific positive transcription factor 1
- PIT-1
- Growth hormone factor 1
- GHF-1
Gene names POU1F1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P28069

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSCQAFTSAD TFIPLNSDAS ATLPLIMHHS AAECLPVSNH ATNVMSTATG LHYSVPSCHY 
        70         80         90        100        110        120 
GNQPSTYGVM AGSLTPCLYK FPDHTLSHGF PPIHQPLLAE DPTAADFKQE LRRKSKLVEE 
       130        140        150        160        170        180 
PIDMDSPEIR ELEKFANEFK VRRIKLGYTQ TNVGEALAAV HGSEFSQTTI CRFENLQLSF 
       190        200        210        220        230        240 
KNACKLKAIL SKWLEEAEQV GALYNEKVGA NERKRKRRTT ISIAAKDALE RHFGEQNKPS 
       250        260        270        280        290    
SQEIMRMAEE LNLEKEVVRV WFCNRRQREK RVKTSLNQSL FSISKEHLEC R

Isoforms

- Isoform A of Pituitary-specific positive transcription factor 1

Sequence View

        10         20         30         40         50         60 
MSCQAFTSAD TFIPLNSDAS ATLPLIMHHS AAECLPVSNH ATNVMSTATG LHYSVPSCHY 
        70         80         90        100        110        120 
GNQPSTYGVM AGSLTPCLYK FPDHTLSHGF PPIHQPLLAE DPTAADFKQE LRRKSKLVEE 
       130        140        150        160        170        180 
PIDMDSPEIR ELEKFANEFK VRRIKLGYTQ TNVGEALAAV HGSEFSQTTI CRFENLQLSF 
       190        200        210        220        230        240 
KNACKLKAIL SKWLEEAEQV GALYNEKVGA NERKRKRRTT ISIAAKDALE RHFGEQNKPS 
       250        260        270        280        290    
SQEIMRMAEE LNLEKEVVRV WFCNRRQREK RVKTSLNQSL FSISKEHLEC R



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P28069-1-unknown MSCQAF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P28069-1-unknown MSCQAF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt85258

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HLECR 291 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HLECR 291 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt80876

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)