P28241: Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial
| Protein names | - Isocitrate dehydrogenase NAD] subunit 2, mitochondrial - 1.1.1.41 - Isocitric dehydrogenase - NAD(+)-specific ICDH |
|---|---|
| Gene names | IDH2 |
| Organism | Saccharomyces cerevisiae |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P28241 |
3
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLRNTFFRNT SRRFLATVKQ PSIGRYTGKP NPSTGKYTVS FIEGDGIGPE ISKSVKKIFS
70 80 90 100 110 120
AANVPIEWES CDVSPIFVNG LTTIPDPAVQ SITKNLVALK GPLATPIGKG HRSLNLTLRK
130 140 150 160 170 180
TFGLFANVRP AKSIEGFKTT YENVDLVLIR ENTEGEYSGI EHIVCPGVVQ SIKLITRDAS
190 200 210 220 230 240
ERVIRYAFEY ARAIGRPRVI VVHKSTIQRL ADGLFVNVAK ELSKEYPDLT LETELIDNSV
250 260 270 280 290 300
LKVVTNPSAY TDAVSVCPNL YGDILSDLNS GLSAGSLGLT PSANIGHKIS IFEAVHGSAP
310 320 330 340 350 360
DIAGQDKANP TALLLSSVMM LNHMGLTNHA DQIQNAVLST IASGPENRTG DLAGTATTSS
FTEAVIKRL
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P28241-15-unknown | LATVKQ... | 15 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32128 | |||
| P28241-15-unknown | LATVKQ... | 15 | unknown | Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... | 19837041 | ||||
| P28241-16-unknown | ATVKQP... | 16 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P28241-16-unknown | ATVKQP... | 16 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31995 | |||
| P28241-16-unknown | ATVKQP... | 16 | unknown | Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... | 19837041 | ||||
| P28241-17-unknown | TVKQPS... | 17 | unknown | Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... | 19837041 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...TSRRFL | 14 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32128 | |||
| ...SRRFLA | 15 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31995 | |||
| ...VIKRL | 369 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MPPB_YEAST | 14 | RRFL.|.LATV | inferred from experiment | unknown | MEROPS | Meisinger C | Vogtle FN et al.:Global analysis of the mitochon... (M24.026) | 19837041, |
| ICP55_YEAST | 15 | RFLA.|.ATVK | inferred from experiment | unknown | MEROPS | Meisinger C | Vogtle FN et al.:Global analysis of the mitochon... (M24.026) | 19837041, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|