TopFIND 4.0

P28309: Alpha-defensin 2

General Information

Protein names	- Alpha-defensin 2 - Cryptdin-1 - Defensin-related cryptdin-2
Gene names	Defa2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P28309

3

N-termini

2

C-termini

2

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MKPLVLLSAL VLLSFQVQAD PIQNTDEETK TEEQSGEEDQ AVSVSFGDRE GASLQEESLR
70 80 90
DLVCYCRTRG CKRRERMNGT CRKGHLMYTL CCR

Isoforms

Sequence View

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P28309-20-unknown	DPIQNT...	20		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P28309-44-unknown	VSFGDR...	44		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34442
P28309-54-unknown	LQEESL...	54		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34443

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...DQAVSV	43	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34442
	...REGASL	53	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34443

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP7_MOUSE	43	AVSV.\|.VSFG	inferred from experiment	unknown	MEROPS	Ouellette AJ	Shirafuji Y et al.:Structural determinants of proc... (M10.008)	12482850,
MMP7_MOUSE	53	GASL.\|.LQEE	inferred from experiment	unknown	MEROPS	Ouellette AJ	Shirafuji Y et al.:Structural determinants of proc... (M10.008)	12482850,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)