TopFIND 4.0

P28335: 5-hydroxytryptamine receptor 2C

General Information

Protein names
- 5-hydroxytryptamine receptor 2C
- 5-HT-2C
- 5-HT2C
- 5-HTR2C
- 5-hydroxytryptamine receptor 1C
- 5-HT-1C
- 5-HT1C
- Serotonin receptor 2C
Gene names HTR2C
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P28335

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVNLRNAVHS FLVHLIGLLV WQCDISVSPV AAIVTDIFNT SDGGRFKFPD GVQNWPALSI 
        70         80         90        100        110        120 
VIIIIMTIGG NILVIMAVSM EKKLHNATNY FLMSLAIADM LVGLLVMPLS LLAILYDYVW 
       130        140        150        160        170        180 
PLPRYLCPVW ISLDVLFSTA SIMHLCAISL DRYVAIRNPI EHSRFNSRTK AIMKIAIVWA 
       190        200        210        220        230        240 
ISIGVSVPIP VIGLRDEEKV FVNNTTCVLN DPNFVLIGSF VAFFIPLTIM VITYCLTIYV 
       250        260        270        280        290        300 
LRRQALMLLH GHTEEPPGLS LDFLKCCKRN TAEEENSANP NQDQNARRRK KKERRPRGTM 
       310        320        330        340        350        360 
QAINNERKAS KVLGIVFFVF LIMWCPFFIT NILSVLCEKS CNQKLMEKLL NVFVWIGYVC 
       370        380        390        400        410        420 
SGINPLVYTL FNKIYRRAFS NYLRCNYKVE KKPPVRQIPR VAATALSGRE LNVNIYRHTN 
       430        440        450    
EPVIEKASDN EPGIEMQVEN LELPVNPSSV VSERISSV

Isoforms

- Isoform 2 of 5-hydroxytryptamine receptor 2C

Sequence View

        10         20         30         40         50         60 
MVNLRNAVHS FLVHLIGLLV WQCDISVSPV AAIVTDIFNT SDGGRFKFPD GVQNWPALSI 
        70         80         90        100        110        120 
VIIIIMTIGG NILVIMAVSM EKKLHNATNY FLMSLAIADM LVGLLVMPLS LLAILYDYVW 
       130        140        150        160        170        180 
PLPRYLCPVW ISLDVLFSTA SIMHLCAISL DRYVAIRNPI EHSRFNSRTK AIMKIAIVWA 
       190        200        210        220        230        240 
ISIGVSVPIP VIGLRDEEKV FVNNTTCVLN DPNFVLIGSF VAFFIPLTIM VITYCLTIYV 
       250        260        270        280        290        300 
LRRQALMLLH GHTEEPPGLS LDFLKCCKRN TAEEENSANP NQDQNARRRK KKERRPRGTM 
       310        320        330        340        350        360 
QAINNERKAS KVLGIVFFVF LIMWCPFFIT NILSVLCEKS CNQKLMEKLL NVFVWIGYVC 
       370        380        390        400        410        420 
SGINPLVYTL FNKIYRRAFS NYLRCNYKVE KKPPVRQIPR VAATALSGRE LNVNIYRHTN 
       430        440        450    
EPVIEKASDN EPGIEMQVEN LELPVNPSSV VSERISSV



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P28335-1-unknown MVNLRN... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65790
    P28335-33-unknown IVTDIF... 33 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P28335-33-unknown IVTDIF... 33 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt115061

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RISSV 458 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)