TopFIND 4.0

P28492: Glutaminase liver isoform, mitochondrial

General Information

Protein names
- Glutaminase liver isoform, mitochondrial
- GLS
- 3.5.1.2 {ECO:0000250|UniProtKB:Q571F8}
- L-glutaminase
- L-glutamine amidohydrolase
Gene names Gls2
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P28492

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRSMRALQNA LSRAGSHGQR GGWGHPSRGP LLGGGVRYYF GEAAAQGRGT PHSHQPQHSD 
        70         80         90        100        110        120 
HDASNSGMLP RLGDLLFYTI AEGQERIPIH KFTTALKATG LQTSDPRLQD CMSKMQRMVQ 
       130        140        150        160        170        180 
ESSSGGLLDR ELFQKCVSSN IVLLTQAFRK KFVIPDFEEF TGHVDRIFED AKELTGGKVA 
       190        200        210        220        230        240 
AYIPHLAKSN PDLWGVSLCT VDGQRHSVGH TKIPFCLQSC VKPLTYAISV STLGTDYVHK 
       250        260        270        280        290        300 
FVGKEPSGLR YNKLSLNEEG IPHNPMVNAG AIVVSSLIKM DCNKAEKFDF VLQYLNKMAG 
       310        320        330        340        350        360 
NEFMGFSNAT FQSEKETGDR NYAIGYYLKE KKCFPKGVDM MAALDLYFQL CSVEVTCESG 
       370        380        390        400        410        420 
SVMAATLANG GICPITGESV LSAEAVRNTL SLMHSCGMYD FSGQFAFHVG LPAKSAVSGA 
       430        440        450        460        470        480 
ILLVVPNVMG MMCLSPPLDK LGNSHRGISF CQKLVSLFNF HNYDNLRHCA RKLDPRREGG 
       490        500        510        520        530        540 
EVRNKTVVNL LFAAYSGDVS ALRRFALSAV DMEQKDYDSR TALHVAAAEG HIDVVKFLIE 
       550        560        570        580        590        600 
ACKVNPFVKD RWGNIPLDDA VQFNHLEVVK LLQDYHDSYM LSETQAEVAA ETLSKENLES 
   
MV

Isoforms

- Isoform 2 of Glutaminase liver isoform, mitochondrial

Sequence View

        10         20         30         40         50         60 
MRSMRALQNA LSRAGSHGQR GGWGHPSRGP LLGGGVRYYF GEAAAQGRGT PHSHQPQHSD 
        70         80         90        100        110        120 
HDASNSGMLP RLGDLLFYTI AEGQERIPIH KFTTALKATG LQTSDPRLQD CMSKMQRMVQ 
       130        140        150        160        170        180 
ESSSGGLLDR ELFQKCVSSN IVLLTQAFRK KFVIPDFEEF TGHVDRIFED AKELTGGKVA 
       190        200        210        220        230        240 
AYIPHLAKSN PDLWGVSLCT VDGQRHSVGH TKIPFCLQSC VKPLTYAISV STLGTDYVHK 
       250        260        270        280        290        300 
FVGKEPSGLR YNKLSLNEEG IPHNPMVNAG AIVVSSLIKM DCNKAEKFDF VLQYLNKMAG 
       310        320        330        340        350        360 
NEFMGFSNAT FQSEKETGDR NYAIGYYLKE KKCFPKGVDM MAALDLYFQL CSVEVTCESG 
       370        380        390        400        410        420 
SVMAATLANG GICPITGESV LSAEAVRNTL SLMHSCGMYD FSGQFAFHVG LPAKSAVSGA 
       430        440        450        460        470        480 
ILLVVPNVMG MMCLSPPLDK LGNSHRGISF CQKLVSLFNF HNYDNLRHCA RKLDPRREGG 
       490        500        510        520        530        540 
EVRNKTVVNL LFAAYSGDVS ALRRFALSAV DMEQKDYDSR TALHVAAAEG HIDVVKFLIE 
       550        560        570        580        590        600 
ACKVNPFVKD RWGNIPLDDA VQFNHLEVVK LLQDYHDSYM LSETQAEVAA ETLSKENLES 
   
MV



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Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P28492-15-unknown GSHGQR... 15 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P28492-68-unknown MLPRLG... 68 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192696

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LESMV 602 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LESMV 602 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152642

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)