TopFIND 4.0

P28649: Aromatase

General Information

Protein names
- Aromatase
- 1.14.14.14 {ECO:0000250|UniProtKB:P11511}
- CYPXIX
- Cytochrome P-450AROM
- Cytochrome P450 19A1
- Estrogen synthase
Gene names Cyp19a1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P28649

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFLEMLNPMQ YNVTIMVPET VTVSAMPLLL IMGLLLLIWN CESSSSIPGP GYCLGIGPLI 
        70         80         90        100        110        120 
SHGRFLWMGI GSACNYYNKM YGEFMRVWIS GEETLIISKS SSMFHVMKHS HYISRFGSKR 
       130        140        150        160        170        180 
GLQCIGMHEN GIIFNNNPSL WRTIRPFFMK ALTGPGLVRM VEVCVESIKQ HLDRLGEVTD 
       190        200        210        220        230        240 
TSGYVDVLTL MRHIMLDTSN MLFLGIPLDE SAIVKKIQGY FNAWQALLIK PNIFFKISWL 
       250        260        270        280        290        300 
YRKYERSVKD LKDEIAVLVE KKRHKVSTAE KLEDCMDFAT DLIFAERRGD LTKENVNQCI 
       310        320        330        340        350        360 
LEMLIAAPDT MSVTLYFMLL LVAEYPEVEA AILKEIHTVV GDRDIKIEDI QNLKVVENFI 
       370        380        390        400        410        420 
NESMRYQPVV DLVMRRALED DVIDGYPVKK GTNIILNIGR MHRLEYFPKP NEFTLENFEK 
       430        440        450        460        470        480 
NVPYRYFQPF GFGPRGCAGK YIAMVMMKVV LVTLLRRFQV KTLQKRCIEN IPKKNDLSLH 
       490        500    
PNEDRHLVEI IFSPRNSDKY LQQ

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P28649-1-unknown MFLEML... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KYLQQ 503 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)