P28838: Cytosol aminopeptidase

General Information

Protein names	- Cytosol aminopeptidase - 3.4.11.1 - Leucine aminopeptidase 3 - LAP-3 - Leucyl aminopeptidase - Peptidase S - Proline aminopeptidase - 3.4.11.5 - Prolyl aminopeptidase
Gene names	LAP3
Organism	Homo sapiens
Protease Family
Protease ID	M17.001
Chromosome location
UniProt ID	P28838

8 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MFLLPLPAAG RVVVRRLAVR RFGSRSLSTA DMTKGLVLGI YSKEKEDDVP QFTSAGENFD
        70         80         90        100        110        120
KLLAGKLRET LNISGPPLKA GKTRTFYGLH QDFPSVVLVG LGKKAAGIDE QENWHEGKEN
       130        140        150        160        170        180
IRAAVAAGCR QIQDLELSSV EVDPCGDAQA AAEGAVLGLY EYDDLKQKKK MAVSAKLYGS
       190        200        210        220        230        240
GDQEAWQKGV LFASGQNLAR QLMETPANEM TPTRFAEIIE KNLKSASSKT EVHIRPKSWI
       250        260        270        280        290        300
EEQAMGSFLS VAKGSDEPPV FLEIHYKGSP NANEPPLVFV GKGITFDSGG ISIKASANMD
       310        320        330        340        350        360
LMRADMGGAA TICSAIVSAA KLNLPINIIG LAPLCENMPS GKANKPGDVV RAKNGKTIQV
       370        380        390        400        410        420
DNTDAEGRLI LADALCYAHT FNPKVILNAA TLTGAMDVAL GSGATGVFTN SSWLWNKLFE
       430        440        450        460        470        480
ASIETGDRVW RMPLFEHYTR QVVDCQLADV NNIGKYRSAG ACTAAAFLKE FVTHPKWAHL
       490        500        510
DIAGVMTNKD EVPYLRKGMT GRPTRTLIEF LLRFSQDNA

Isoforms

- Isoform 2 of Cytosol aminopeptidase

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P28838-1-unknown	MFLLPL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P28838-27-unknown	LSTADM...	27		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P28838-27-	LSTADM...	27		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_CD95	23264352
P28838-27-	LSTADM...	27		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P28838-28-	STADMT...	28		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P28838-28-	STADMT...	28		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P28838-28-	STADMT...	28		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P28838-28-	STADMT...	28		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P28838-28-unknown	STADMT...	28		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P28838-32-unknown	MTKGLV...	32	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66823
P28838-32-unknown	MTKGLV...	32	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P28838-225-	SASSKT...	225		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P28838-225-unknown	SASSKT...	225	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178488

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...SQDNA	519	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...SQDNA	519	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt62441

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)