TopFIND 4.0

P30182: DNA topoisomerase 2

General Information

Protein names
- DNA topoisomerase 2
- 5.6.2.3 {ECO:0000255|PROSITE-ProRule:PRU00995}
- DNA topoisomerase II
Gene names TOP2
Organism Arabidopsis thaliana
Protease Family
Protease ID
Chromosome location
UniProt ID P30182

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATKLPLQNS NAANVAKAPA KSRAAAGGKT IEEMYQKKSQ LEHILLRPDT YIGSIEKHTQ 
        70         80         90        100        110        120 
TLWVYEKDEM VQRPVTYVPG LYKIFDEILV NAADNKQRDA KMDSVQVVID VEQNLISVCN 
       130        140        150        160        170        180 
SGAGVPVEIH QEEGIYVPEM IFGHLLTSSN YDDNVKKTTG GRNGYGAKLT NIFSTEFIIE 
       190        200        210        220        230        240 
TADGKRLKKY KQVFENNMGK KSEPVITKCN KSENWTKVTF KPDLKKFNMT ELEDDVVALM 
       250        260        270        280        290        300 
SKRVFDIAGC LGKSVKVELN GKQIPVKSFT DYVDLYLSAA NKSRTEDPLP RLTEKVNDRW 
       310        320        330        340        350        360 
EVCVSLSEGQ FQQVSFVNSI ATIKGGTHVD YVTSQITNHI VAAVNKKNKN ANVKAHNVKN 
       370        380        390        400        410        420 
HLWVFVNALI DNPAFDSQTK ETLTLRQSSF GSKCELSEDF LKKVGKSGVV ENLLSWADFK 
       430        440        450        460        470        480 
QNKDLKKSDG AKTGRVLVEK LDDAAEAGGK NSRLCTLILT EGDSAKSLAL AGRSVLGNNY 
       490        500        510        520        530        540 
CGVFPLRGKL LNVREASTTQ ITNNKEIENL KKILGLKQNM KYENVNSLRY GQMMIMTDQD 
       550        560        570        580        590        600 
HDGSHIKGLL INFIHSFWPS LLQVPSFLVE FITPIVKATR KGTKKVLSFY SMPEYEEWKE 
       610        620        630        640        650        660 
SLKGNATGWD IKYYKGLGTS TAEEGKEYFS NLGLHKKDFV WEDEQDGEAI ELAFSKKKIE 
       670        680        690        700        710        720 
ARKNWLSSYV PGNHLDQRQP KVTYSDFVNK ELILFSMADL QRSIPSMVDG LKPGQRKILF 
       730        740        750        760        770        780 
VAFKKIARKE MKVAQLVGYV SLLSAYHHGE QSLASAIIGM AQDYVGSNNI NLLLPNGQFG 
       790        800        810        820        830        840 
TRTSGGKDSA SARYIFTKLS PVTRILFPKD DDLLLDYLNE DGQRIEPTWY MPIIPTVLVN 
       850        860        870        880        890        900 
GAEGIGTGWS TFIPNYNPRE IVANVRRLLN GESMVPMDPW YRGFKGTIEK TASKEGGCTY 
       910        920        930        940        950        960 
TITGLYEEVD ETTIRITELP IRRWNDDYKN FLQSLKTDNG APFFQDVKAY NDEKSVDFDL 
       970        980        990       1000       1010       1020 
ILSEENMLAA RQEGFLKKFK LTTTIATSNM HLFDKKGVIK KYVTPEQILE EFFDLRFEYY 
      1030       1040       1050       1060       1070       1080 
EKRKETVVKN MEIELLKLEN KARFILAVLS GEIIVNKRKK ADIVEDLRQK GFTPFPRKAE 
      1090       1100       1110       1120       1130       1140 
SVEAAIAGAV DDDAAEEPEE ILVDPESSSS YIPGSEYDYL LAMAIASLTI EKVEELLADR 
      1150       1160       1170       1180       1190       1200 
DKMIIAVADM KKTTPKSLWL SDLESLDKEL EKLDLKDAQV QQAIEAAQKK IRAKSGAAVK 
      1210       1220       1230       1240       1250       1260 
VKRQAPKKPA PKKTTKKASE SETTEASYSA MDTDNNVAEV VKPKARQGAK KKASESETTE 
      1270       1280       1290       1300       1310       1320 
ASHSAMDTDN NVAEVVKPKG RQGAKKKAPA AAKEVEEDEM LDLAQRLAQY NFGSAPADSS 
      1330       1340       1350       1360       1370       1380 
KTAETSKAIA VDDDDDDVVV EVAPVKKGGR KPAATKAAKP PAAPRKRGKQ TVASTEVLAI 
      1390       1400       1410       1420       1430       1440 
GVSPEKKVRK MRSSPFNKKS SSVMSRLADN KEEESSENVA GNSSSEKSGG DVSAISRPQR 
      1450       1460       1470    
ANRRKMTYVL SDSESESAND SEFDDIEDDE DDE

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P30182-1-unknown MATKLP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DEDDE 1473 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)