TopFIND 4.0

P30304: M-phase inducer phosphatase 1

General Information

Protein names
- M-phase inducer phosphatase 1
- 3.1.3.48
- Dual specificity phosphatase Cdc25A
Gene names CDC25A
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P30304

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MELGPEPPHR RRLLFACSPP PASQPVVKAL FGASAAGGLS PVTNLTVTMD QLQGLGSDYE 
        70         80         90        100        110        120 
QPLEVKNNSN LQRMGSSEST DSGFCLDSPG PLDSKENLEN PMRRIHSLPQ KLLGCSPALK 
       130        140        150        160        170        180 
RSHSDSLDHD IFQLIDPDEN KENEAFEFKK PVRPVSRGCL HSHGLQEGKD LFTQRQNSAP 
       190        200        210        220        230        240 
ARMLSSNERD SSEPGNFIPL FTPQSPVTAT LSDEDDGFVD LLDGENLKNE EETPSCMASL 
       250        260        270        280        290        300 
WTAPLVMRTT NLDNRCKLFD SPSLCSSSTR SVLKRPERSQ EESPPGSTKR RKSMSGASPK 
       310        320        330        340        350        360 
ESTNPEKAHE TLHQSLSLAS SPKGTIENIL DNDPRDLIGD FSKGYLFHTV AGKHQDLKYI 
       370        380        390        400        410        420 
SPEIMASVLN GKFANLIKEF VIIDCRYPYE YEGGHIKGAV NLHMEEEVED FLLKKPIVPT 
       430        440        450        460        470        480 
DGKRVIVVFH CEFSSERGPR MCRYVRERDR LGNEYPKLHY PELYVLKGGY KEFFMKCQSY 
       490        500        510        520    
CEPPSYRPMH HEDFKEDLKK FRTKSRTWAG EKSKREMYSR LKKL

Isoforms

- Isoform 2 of M-phase inducer phosphatase 1

Sequence View

        10         20         30         40         50         60 
MELGPEPPHR RRLLFACSPP PASQPVVKAL FGASAAGGLS PVTNLTVTMD QLQGLGSDYE 
        70         80         90        100        110        120 
QPLEVKNNSN LQRMGSSEST DSGFCLDSPG PLDSKENLEN PMRRIHSLPQ KLLGCSPALK 
       130        140        150        160        170        180 
RSHSDSLDHD IFQLIDPDEN KENEAFEFKK PVRPVSRGCL HSHGLQEGKD LFTQRQNSAP 
       190        200        210        220        230        240 
ARMLSSNERD SSEPGNFIPL FTPQSPVTAT LSDEDDGFVD LLDGENLKNE EETPSCMASL 
       250        260        270        280        290        300 
WTAPLVMRTT NLDNRCKLFD SPSLCSSSTR SVLKRPERSQ EESPPGSTKR RKSMSGASPK 
       310        320        330        340        350        360 
ESTNPEKAHE TLHQSLSLAS SPKGTIENIL DNDPRDLIGD FSKGYLFHTV AGKHQDLKYI 
       370        380        390        400        410        420 
SPEIMASVLN GKFANLIKEF VIIDCRYPYE YEGGHIKGAV NLHMEEEVED FLLKKPIVPT 
       430        440        450        460        470        480 
DGKRVIVVFH CEFSSERGPR MCRYVRERDR LGNEYPKLHY PELYVLKGGY KEFFMKCQSY 
       490        500        510        520    
CEPPSYRPMH HEDFKEDLKK FRTKSRTWAG EKSKREMYSR LKKL



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P30304-1-unknown MELGPE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P30304-1-unknown MELGPE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81454

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RLKKL 524 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RLKKL 524 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt77072

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)